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Old 09-14-2015, 08:25 AM #1
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Cholinergic neuropathy is like a subset of autonomic neuropathy and has many of the same symptoms. The most common are extreme dry mouth/eyes, lack of sweating and GI dysmotility.

Here's a link that gives some info on various autonomic neuropathies...including cholinergic neuropathy.

http://www.medmerits.com/index.php/a...europathies/P2

Do you have very dry eyes/mouth and problems sweating and GI upset?
I have dry eyes and mouth and nose. Are they extreme? I don't know... I'm constantly rubbing my eyes, drinking water and trying to clear my nose. Do these things make me not functional? No. More annoying than anything else. My nose is clogged with boogers and it feels swollen inside like my nostrils are closing.

I have no idea about whether my bowels are different or not. I've always had issues where I get bouts of something similar to ibs. Am I constiapated? I don't know... There are days when I don't "go" but it doesn't bother me. Sometimes I get the " opposite" happening. But none of this bothers me and I don't really keep track of my movements. I mean isn't everybody like that? I Don't know... Does everybody go everyday? I guess I'm tying to say o don't know if I have an issue. Would u definitely know if u did?
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Old 09-14-2015, 10:07 AM #2
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Canagirl,

Have you had any autonomic testing?

The GI dysmotility is not just constipation...it's more about motility of the stomach (emptying). It causes early fullness (before you even finish normal size meal), bloating, fullness discomfort, nausea, etc.
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Old 09-14-2015, 10:26 AM #3
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I have dry eyes and mouth and nose. Are they extreme? I don't know... I'm constantly rubbing my eyes, drinking water and trying to clear my nose. Do these things make me not functional? No. More annoying than anything else. My nose is clogged with boogers and it feels swollen inside like my nostrils are closing.

I have no idea about whether my bowels are different or not. I've always had issues where I get bouts of something similar to ibs. Am I constiapated? I don't know... There are days when I don't "go" but it doesn't bother me. Sometimes I get the " opposite" happening. But none of this bothers me and I don't really keep track of my movements. I mean isn't everybody like that? I Don't know... Does everybody go everyday? I guess I'm tying to say o don't know if I have an issue. Would u definitely know if u did?
Yes, You would know if you had issues. Things would bother you.
Eating would be incredibly taxing because your chewing, swallowing, and peristalsis would be impacted. It is terrible. It's not something you would not notice.
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Old 09-14-2015, 11:41 AM #4
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I might be a good idea if you, Healthgirl, get evaluated for myasthenia gravis.

Chewing and breathing are impacted by this autoimmune disease too. The neuromuscular junction runs on acetylcholine, and is affected by autoimmune antibodies.

We have an MG forum here on NT.

Here is their list of drugs to avoid:
http://dig.pharm.uic.edu/faq/myasthenia.aspx
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Old 09-15-2015, 10:30 AM #5
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I might be a good idea if you, Healthgirl, get evaluated for myasthenia gravis.

Chewing and breathing are impacted by this autoimmune disease too. The neuromuscular junction runs on acetylcholine, and is affected by autoimmune antibodies.

We have an MG forum here on NT.

Here is their list of drugs to avoid:
http://dig.pharm.uic.edu/faq/myasthenia.aspx
My symtoms are all consistent with myasthenia but Weil Cornell and NY Presbyterian, I haven't been diagnosed with it. So far all they can find is the cholinergic neuropathy and significantly reduced fiber density from my thigh (worse than my ankle). So I guess that means non length dependent. My doctor does put on my report that the neck problems are not consistent with SFN, but gives absolutely no insight into that. My neck and arms are what landed me in the emergency room a year ago yesterday.
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Old 09-14-2015, 11:33 PM #6
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Yes, You would know if you had issues. Things would bother you.
Eating would be incredibly taxing because your chewing, swallowing, and peristalsis would be impacted. It is terrible. It's not something you would not notice.

For once I can say I don't have these symptoms! That sounds terrible. I hope these symptoms improve for you
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Old 09-15-2015, 03:40 AM #7
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For once I can say I don't have these symptoms! That sounds terrible. I hope these symptoms improve for you
Autonomic affects more of your organs, like sweating, full or empty bladder, moisture secretion, your Gi system(constipation, gastroparesis)is affected as well. Pn is only your sensory nerves/twitching. the burning, itching, pins and needles,,,etc. are all PN.
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