Thanks for this, Glenn.

Yes, this: given the immune function of the gut, dysregulation there might lead to autoimmunities with neuropathy as a symptom.

Also what you say about alcohol is spot on. Moreover, drinking lots of beer can cause dybiosis in the gut, so there's that. I want to set things right in my gut and see what happens.

I've posted elsewhere about this, but I've had lots of blood tests, including ANA, which came back negative. I'll look through Liza Jane's sheets and see what else I can do. I want to test for mold and other toxins, since I suspect something along those lines, but I'm not sure what tests I can get done here in Canada.

I've had the tests for Celiac, but since I haven't had gluten for months, that came back negative. I may never know it's gluten, if it is that. I hear there's some test in the works that requires only 2-3 days of gluten exposure. But there's no way I'm going to eat gluten for months to get tested. I'm having a biopsy in the spring by my GI, but that will come back negative too, given my lack of exposure.

I do have IBS, so there might be something going on in the gut, likely so, made worse by the beer, the yeast and grain, and possibly some toxin or something that has caused infection and systematic inflammation.

Amyloidosis is also a possibility. I do have relatively low B12, but not deficient according to conventional standards. My D was quite low though. Anyway ideas and suggestions are certainly welcome, and thanks again.

Have you tested for helicobacter pylori ?
Have you tried to reduce the salt intake ?

H pylori can reduce B12 and other nutrients absorption
Sodium increases the activity of H pylori and irritates the gut.

Thanks, Stillhoping. No, I haven't tested for it but have suspected it in the past. I'll bring it up with my GP when I see her in the new few weeks. I consume lots of salt, good sea salt, and don't feel any worse, so I don't know. My GP did do a parasites and bacteria stool test a few months back, but that tests only for the most common things, and I don't believe HP can be tested that way, if I recall correctly.

I have used the pro-biotic oral sprays. They have helped, i can't stand yogurt (if not sweetened) so its a better bet for me.

My favourite yogurt is plain, sour yogurt, so just naturally fermented so to speak, and so very high in probiotics. But I don't eat dairy anymore. Now I get my probiotics from sauerkraut, and will soon ferment all sorts of my own veggies. But I've also been meaning to check out Custom Probiotics as I posted here: http://neurotalk.psychcentral.com/sh...02#post1190902

I started to keep on a healthy nutrition with very low salt intake more than 10 years ago. I tried a few times (before this nutrition, and again recently) a treatment to POTS with high salt intake (2000-3000mg sodium for day).
The salt increased my dryness and caused many gut symptoms, it improved greatly when I stopped the treatment and reduced the salt.

Interesting. I wonder if certain of my symptoms would disappear from reduced salt. What kind of salt were you consuming? I've so far seen no connection between my salt intake and symptoms, but plenty with glucose.

As far as I remember from your posts, my nutrition is very different then yours. I am vegan, I eat veggetables, fruits, unprocessed carbs, legumes, nuts and grains. Almost no processed, fried or smoked food, I hardly add salt to my food (I guess my daily sodium consumption is about 500mg), or eat spicy food. I get most of my fluids from the veggie and fruits so I don't drink much.
When I started this diet all the Sjogren's like symptoms improved/disappeared and I thought for a while that I was cured.
I stopped using eye drops (I had punctal plugs and used to put eye drops and gel many times each day), the dry skin, nose and skin greatly improved, the joint and muscle ache, and the low grade fever disappeared, the POTS improved and I had more energy.

But I still developed Lymphoma, SFN, and debilitating fatigue despite of many years with that nutrition...
Who knows whether the nutrition helped or not with these.... I don't have a control group...

Right, that's true. My diet is paleo ketogenic. I consume plenty of quality sea salt, almost entirely pink Himalayan salt. I wonder how you'd do on such a diet. I wonder how I'd do with less salt. My face symptoms have gotten worse, but that could also be due to the cold weather, which especially affects my eyes and the watering.

I'm sorry you continue to develop such health problems, and as I've said before I hope you find relief soon. Keep hoping! I don't know what the future holds for me, but I do hope I keep improving. I don't know what to make of some of my symptoms that seem to be getting worse. My energy levels are much better though since I've been supplementing with B12 and B complex.