Unfortnately I was unable to tolerate Lyrica - it made me very angry and dizzy. Same for Gaberpentin and Amitiptyline finally gave me severe palpitations after three good years. Cymbalta triggered a whole host of horrible infections for me last year when I came off it. So for me, and many others I believe, these masking drugs aren't an option. Nor are the four DMARDs I've taken and had severe allergic reactions to. Naproxen helps me a lot but after three days my tummy kicks off with GERD so NSAIDs are not a long term option for me.

I'm taking Levothyroxine, Losartan and newly on Amlodopine. I started to swell in the face last week with what I recognised as an allergic reaction after two lots of anaphylaxis from DMARDs. So I was taken off it and restating it today. My face is red and hot but I'm hanging in there as really hate the idea of soaring blood pressure. It's an endless tightrope for many people between medication and symptoms but I'm resolved that for me personally, there has to be a cause for my ever progressing SFN and if this can be established there might also be a treatment I can tolerate. More researchers like yourself are needed and more focus on the nervous system and autoimmunity in my opinion. But I realise I'm bias!