I agree - I think I'm much more like you in the way my neuropathy is progressing than a typical Sjogrens sufferer Enbloc. I don't have the dry mouth now and I don't actually have dry eyes any longer since coming off those drugs I mentioned -but like my scalp and back they feel dry if this makes any sense? I have a frantically itchy scalp and a spot on my back and these dry eyes that feel as if I have no tears.

But when my optician tested my eyes he said there didn't seem to be any particular sigh of blepharitis and when my scalp has been checked I gave no sign of dandruff, skin doesn't look especially dry on my back and yet the itch is insane! And, having suffered from severe eczema and allergies and blepharitis all through the first four decades of my life I know the difference. The only reason I think that I do have the neuro type of Sjogrens is historic. I have such a long history of dryness and then two years of synovitis/RA that it seems more likely than some random idiopathic neuropathy.

It is VERY confusing but I think you are very right to distinguish between the severe dryness DavidH describes and the dryness caused by PN/AN/ sensory polyneuropathy. I would love to be offered IViG for mine I must say. I did ask but, like Healthgirl I have been told that the only treatment for Sjogrens is Hydroxichloraquine/ Plaquenil - which I took for 18 months but finally couldn't tolerate (urticaria/ angioderma).

So maybe you can ask for IVIG ?

I had severe dryness (got punctual plugs in the eyes, had nose bleeds, had to drink to swallow dry food, used tons of eye drops and gel, moisturizing creams, etc.) with negative antibodies and negative lip biopsy. When it started I had fatigue and joint pain and neurological peripheral problems POTS (not severe), Adie tonic pupil, trigeminal neuralgia.
15+ years later the antibodies for Sjogren are still negative, the dryness improved greatly since I started a healthy nutrition, and a few years ago I got SFN.

So it seems I got something neurological autoimmune, I don’t know if I have got seronegative Sjogren, or that my dryness is affected by my autonomic neuropathy.

Are there any tests that can prove that the dryness is caused by autonomic neuropathy ?

Insurance won't accept my criteria.

And you know whats funny? Well not really funny, but I'd rather laugh then cry... The doctor who wants me to take plaquenil is a neuromuscular neurologist who is the one who does the diagnosing of SFN at Columbia NYC. My symptoms are all 100% neuropathic. I have no swelling of joints or anything that tells me I would get relief from Plaquenil as far as what I've read from other Sjogren's patients. So thanks for this...and sorry David for the hijack.

Newly diagosed – scared beyond belief