Where did you find this info? Also where would I find the info on the group of individuals who say it is working??. Thanks

Sophie look under the link Marlene posted. Then request to join the group. That's what I did.

Thanks. I will check this out

Hi! I'm a moderator for the group in question (my fb name is Kari Kelley) and the protocol, along with diet changed has helped me. We have a lot of members that have had very good results. I have autoimmune mediated neuropathy so I am fighting the current, but for those who are looking to heal damage the supplements and hempseed oil does help.

R-ALA, formally α-lipoic acid, is (through well-understood physiology) a cofactor for some enzymes, notably the pyruvate dehydrogenase complex, the 2-oxoglutarate dehydrogenase complex, branched-chain oxoacid dehydrogenase complex and the acetoin dehydrogenase complex.

The link above asserts, with no evidence, that some OTC forms of R-ALA, taken by mouth, are helpful for neuropathy but others are not. For example, one commercially available form of R-ALA is rejected on the grounds that "it is not 100% sodium stabilized". This sounds very scientific but is meaningless.

If people with neuropathy choose to self-medicate with R-ALA taken by mouth that is their call. However, they should do so in the knowledge that there is no good evidence that it will help.

These issues are discussed in more detail here Lipoic Acid | Linus Pauling Institute | Oregon State University.

ALA was the one nutrient my husband took that had the greatest impact on his PN. R-ALA was not available back then. We decided to tried the ALA based on how they were using it Germany for diabetic PN. I think they dosed at 900 mg/day.

If memory serves me correctly, John's pain level dropped from an 8 to about the 3-5 range within weeks of starting ALA.

It's certainly worth trying. The only concern I had was with higher dose and how it may impact mercury detoxification. It could mobilize more mercury than your body can handle. But John did fine with it.

Interesting thought about the mercury Marlene. Does R-ALA keep mercury from being excreted from your body?

I am laid up in bed with a frozen left knee so this will be
brief.

I see some issues with this "protocol".
The use of this term bothers me.

The massive dose of NaRALA without documentation of saftey
is problematic. I found side effects of A-fib on line for ALA
and also racing heart and insomnia.

ALA shares a transporter with biotn and iodide. This creates
potential issues too.

So do your homework before considering trying this.

Anyone who can get me info on who this is, please PM it
to me.
















r

Thank you If possible could you share your experiences???

Okay... Thanks for that PM Hopeful....

I've managed getting down the stairs so I can now work briefly on my desktop where I can type at my usual speed.

Regarding this "protocol" ... Most of those supplements listed are the same as we use here.

But remember, PN is full of hucksters and people trying to make $$ off of us. The word "protocol" triggers me to think about this posting in that way.

In regards to hemp oil... Here is a link with a chart showing the contents of the various common oils.

Linoleic (C-6) oil is to be avoided. Hence corn, and soybean are less healthy to replenish the Omega-3s because the 6's foster inflammation. The hemp oil show a high 6 content, so I personally would use Flax . Dr. Sears PhD explains the 3-6 ratio of fatty acids and how to keep the inflammatory ones down, and benefit the 3's. So I do not think the Hemp oil is that important, in this list given for PN healing. That is my opinion.
Males do not convert alpha linolenic acid (omega-3) well to the long chains EPA and DHA... females because they carry fetuses, who have large needs for EPA and DHA convert the basic alpha linolenic acid in much higher ratios. The EPA and DHA are anti-inflammatory and very helpful for nerve pain.

Hemp Oil Analysis and Comparison

The biggest concern I have is about the R-lipoic acid dosing etc
It is a massive dosing schedule, and some people will not tolerate it.
Alpha Lipoic Acid supplement benefits and side effects - use for blood sugar, diabetes neuropathy
I took one Doctor's Best NaRALA daily for over a year... no effects for me. When I raised to 2 day in divided doses, I became extremely hyper and irritable, and quickly ramped back down. RALA is mostly useful for prediabetics and diabetics in general, but I never saw any effect with my glucose testing or A1C.

Everyone is different and with supplements most of them are quite benign, but... some are not so benign when you start taking massive doses of them. ALA fits into that category.

I also recommend that you only do high dose supplements after getting liver and kidney testing to show normal functions there.

And also... ALA uses a transporter that is shared by B5 (pantothenic acid), biotin, and iodide. This means that those nutrients may become skewed and not absorbed well if the transporter is flooded with ALA. Biotin and iodide are used in micrograms by the body... that means it doesn't take much interference to affect them and lower their absorption. So long term effects may be seen with deficiencies of these nutrients when the transporter becomes blocked.

Here is more information on the mercury issue, that Marlene kindly added to this thread:
The Surprising Connection Between Alpha Lipoic Acid And Heavy Metal Detox | Take Back Your Health with Robin Shirley

So just be very careful if you decide to follow this FB entry.