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04-07-2020, 07:30 AM | #1 | ||
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Junior Member
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Thank you street legal!
I'm currently trying to find a pharmacy to compound the pirenzipine. This is probably not giong ot happen however because of stupid rules. IF pirenzipine were FDA recognized it would be easy. I've looked into the chemistry, and in the topical studies they used a free base. The pirenzipine you order is HCl, but thats just to make it water soluble and shouldnt affect it very much. I"m thinking I can crush it up, mix it in some DMSO (which makes you absord it), and absorb it that way. The chemist at one of the compounding companies who wanted to help me said this isnt necessarily a crazy idea, although you can never be sure about side effects. Since oxybutin is FDA approved, maybe they will allow us to compound this? My question to you is if this stuff helps rebuild the nerves, it shouldnt matter if its stopped? The results should last, in theory. |
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04-08-2020, 01:19 AM | #2 | ||
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Junior Member
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Quote:
As stated, I stopped using the patches at the worst possible time--just before I embarked on international travel, long-haul flights, and stressful circumstances. I was highly conscious of the stress, both physical and mental, I was putting myself under. And there is no doubt at all that stress is highly embodied for me--even positive emotions set off my paresthesia. That said, if oxybutynin were implicated in healing damaged nerves and not just suppressing symptoms, one would have thought that I would have withstood the stress. In short, within a month of coming off the patches, my symptoms were probably worse than when I had embarked on the experiment, if I am to be brutally honest--that is, pain set in rather than just buzzing and itching. On the other hand, a self-trial of a patch designed for other purposes is hardly an ideal setting, involving a host of variables. |
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06-28-2020, 09:01 PM | #3 | ||
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New Member
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Hi, I think this is a great idea, have you managed to make any progress with this ? Its something that I would love to replicate.
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