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Old 12-30-2007, 04:05 PM #1
elliemae elliemae is offline
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Quote:
Originally Posted by elsie View Post
I have taken Levaquin in the past for bladder infections. I saw where this was posted on their site.

"Rare cases of peripheral neuropathy have been reported in patients receiving quinolones, including levofloxacin. Discontinue if symptoms of neuropathy occur to prevent the development of an irreversible condition."

Does anyone think that levaquin, or this group of antibiotics, caused their PN?
My doctor has diagnosed me with Antibiotic related Neuropathy. Yes, it was the same antibiotic you are taking. My neuropathy has become irreversible. I do not have diabetes so at first it was ideopathic. I had two internal meds and tw Neurologist confirm my conditon from UCLA.

Hope that helps,

Steve
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Old 12-30-2007, 05:05 PM #2
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For the last 6 years i have gotten many respiratory infections, often spaced shortly apart, which is what i am going through right now actually. IM allergic to any cillins so I have been mainly taking biaxin which is very effective for me. In 2002, i was given levaquin at times to switch off from biaxin. It has never been as effective for me as biaxin or zithromax. I know levaquin did not cause my pn since i already had it at that point though i did not know what it was yet. I have never noticed an exacerbation of PN symptoms on levaquin. The pain increases anyway when i get a respiratory infection but got no worse after levaquin use. Then in 2004 in the midst of a cluster of respiratory infections i was prescribed avalox, which is also a quinolone. I had a very bad reaction to avelox, my PN pain went off the charts, it made me nauseous and i was totally out of it. I was hospitalized at that time because of the severity and longevity of infection, wheezing, coughing, etc. and when i went off avelox in the hosptial, the pain returned to its normal level. Since then i have taken levaquin a few times and it has been ineffective but again did not cause additional pain. I have also taken cipro a few times and had no adverse reaction. At this point i wont take any quinolone antibiotics. The point of all this is that i am sure that a particular quinolone can have an effect on peripheral nerves depending on the person.

Steve how did they come to the conclusion that your PN was caused by Levaquin? I have experienced the opposite from doctors, they deny , fudge, or wont make the most obvious cause and effect relationships, even when they see the same thing over and over.
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Old 12-30-2007, 06:30 PM #3
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Thanks, Steve for that interesting information. I am also curious in knowing how the neurologist concluded it was from the levaquin. Is there a way to tell for sure, or is he just assuming?
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Old 12-30-2007, 10:34 PM #4
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Post Cipro is the least obnoxious

of the quinolones. It is not a once a day treatment either.

Levaquin and Avelox are once a day tablets. All of the ones recalled were
also once a day. In general with the exception of Zithromax, once a day
antibiotics tend to be more toxic. There was a once a day sulfonamide called Kynex by Lederle that was taken off the market many years ago.

Cipro still does cause the tendon ruptures however. And those typically happen after the drug is stopped, and months pass. Whatever it is doing takes time
to damage and for a while the ruptures were not connected to Cipro. But when a few doctors had that happen to themselves, it was finally admitted to.
It can happen 6mos after the treatment.

I have really tried to find out how this happens, but I have never seen the mechanism printed out anywhere. I suspect the PN damage is similar, not understood yet.
The fluoroquinolones are very active in the nervous system, so they are doing something there. Floxin was causing seizures for some patients. And the elderly are not recommended to use high doses of any quinolone for this reason.
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Old 12-31-2007, 05:41 AM #5
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I read somewhere the other day that all drugs starting with 'fl'; are either fluoride based or have a significant amount of fluoride in them. I haven't clarified this yet. Can anyone confirm or deny?

Also some theories abound that fluoride may be responsible for the underpinnings of conditions such as CFS/Fibromyalgia. Again I haven't pursued research on this - however I believe empirical evidence must be scarce on the ground - as it is still mandated for usage?
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Old 12-31-2007, 11:09 AM #6
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Lightbulb yes, fluoro--

means a fluoride is there.

Prozac is fluroxitine... and there are several articles on the net about
brain toxicity from fluoride and Prozac.

example:
http://www.antidepressantsfacts.com/...uorophenyl.htm

Since I last looked, there have been many articles added about fluoride affecting thyroid hormone levels.
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Old 01-01-2008, 11:09 AM #7
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"Cipro still does cause the tendon ruptures however. And those typically happen after the drug is stopped, and months pass. Whatever it is doing takes time
to damage and for a while the ruptures were not connected to Cipro. But when a few doctors had that happen to themselves, it was finally admitted to.
It can happen 6mos after..."


Hmmm... Maybe if we had doctors acting as controls in drug testing, we would have a few less toxic medications and ultimately dangerous medical devices rushed to the market... I can think of a few I would like to nominate...

Cathie
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