I know this is not an Alzheimer's forum but I've often thought my PN was an auto-immune disorder. There are lots of signs in our family including Rhematoid arthritis. So when I read this, I thought, "I wonder if this might help PN?" (even if there wasn't auto-immune problems in my family, this seems like such a miracle, I probably would still wonder if it would help me, LOL)

It is an anecdotal story, just one patient:

Researchers at the Donald W. Reynolds Institute on Aging at the University of Arkansas for Medical Sciences (UAMS) gave an Alzheimer's patient an injection of a compound called perispinal etanercept and noticed a "dramatic and unprecedented therapeutic effect" within minutes of the injection.

“It is unprecedented that we can see cognitive and behavioral improvement in a patient with established dementia within minutes of therapeutic intervention,” said [Sue Griffin, Ph.D., director of research at the Donald W. Reynolds Institute on Aging at the University of Arkansas for Medical Sciences (UAMS)]. “It is imperative that the medical and scientific communities immediately undertake to further investigate and characterize the physiologic mechanisms involved. This gives all of us in Alzheimer’s research a tremendous new clue about new avenues of research, which is so exciting and so needed in the field of Alzheimer’s. Even though this report predominantly discusses a single patient, it is of significant scientific interest because of the potential insight it may give into the processes involved in the brain dysfunction of Alzheimer’s.”

More details about drug at:
http://www.jneuroinflammation.com/content/5/1/2