Good morning,


It's been awhile since I last posted. Just a recap....I have PN in legs and feet, axonal small fiber type. Lots of burning, shooting, electric shock, numbing type stuff in legs/feet. Leg cramps, sciatica. Hx of Morton's Neuroma both feet (surgically removed) , alcoholism (will be sober 10 years in 2 days). All major disease screenings have been negative. PN started abruptly 2 years ago.

I am going to see Neuro next Wednesday and just did some bloodwork. I am more than a little concerned about the results. My last bloodwork was all in normal ranges, so this was a little surprising.

I am currently taking:

Prozac
Neurontin
Topamax
Baclofen

Here are the test results I am concerned about. What do you think?

Fasting Glucose 97 (was 76 last year)
HGBA1c 5.6 (was 4.9 last year)
Cholesterol 241 (was 201 last year)
Mean Platelet Value 11.6 (normal range 7.4 - 10.4)

I pretty much think I know where this is heading, but I am shocked that these number could change so drastically in such a short time. I have not changed anything in my lifestyle, my eating habits, etc. Obviously I will be doing so now!

Mrs. D. - could Topamax have anything to do with the spike in cholesterol and the high platelet value?

Thank you...

Ann

anyone? at all?

Ann

Hi Ann,

Not sure I can answer your questions but I just had some thoughts.

Hemo AC1 you want it under a 6.0. I believe this test takes your glucose test one step further. Provides and average glucose levels over the 6 weeks prior to testing. Its more accurate than a fasting glucose where you an be high one day and low the next. Your is still ok but inching up.

Cholesterol is made in the liver, atleast like 70% and the rest roughly from diet. Your cholesterol might be ok depending on the ratio of LDL to HDL. Check your cholesterol ratio by dividing your cholesterol/HDL. UNder 5.0 is still ok.

Could be that your drugs are helping to slow your metabolism.

MrsD can probably add much more but these are just some thoughts.

Hope this helps and

Hmmmm....the mean platlet value could be related to B12 or folate deficiency

Someone else might have a better idea

Hi Ann, I think for Fasting Blood Glucose,
70 to 99 mg/dL (3.9 to 5.5 mmol/L) is normal glucose tolerance,
100 to 125 mg/dL (5.6 to 6.9 mmol/L) Impaired fasting glucose (pre-diabetes),
126 mg/dL (7.0 mmol/L) is classed as Diabetic range.

The 2 hour Oral Glucose Tolerance Test (2 hours after a 75-gram glucose drink)
Less than 140 mg/dL (7.8 mmol/L) Normal glucose tolerance
From 140 to 200 mg/dL (7.8 to 11.1 mmol/L) Impaired glucose tolerance,
Over 200 mg/dL (11.1 mmol/L) Diabetic range.

I will leave the rest to the experts

Brian

--though the inching up pattern is worth keeping an eye on.

The mean platelet value is a measure of platelet size, not count--do you have a platelet count? High mean platelet value is not very specific as a finding; many people have "giant platelets", and often these people have lower platelet counts (though this reading is often skewed by the size of the platelets itself).