Yes, I am pre diabetic and developed neuropathy. I don't know if the
Anodyne Therapy is responsible for my lack on pain but I am thankful
for that. I don't take any meds for neuropathy. I am on a clinical trial
at UT Southwestern here in Dallas. The trial is to administer insulin to avoid full blown diabetes. So my blood glucose is under 110 but the goal of the
trial is to achieve glucose count of 95.

Wow, you're in a clinical trial???

So am I. I'm in the ACCORD program (it's a study to see how controlling one's diabetes, using various methods and meds), can prevent heart attacks and strokes in woman. I go to Cornell Medical Center in NYC.

So far, I'm doing well. And from what I have read, so are you.

Hope you get to your goal.

I have been below 95 with 83 units of insulin taken in the morning.
But the last several weeks I have been on 84 and 85 units of insulin.
I am being closely monitored by a Dr. from India who is in training
to get licensed in U.S. I e-mailed him this morning with over 95
units the last three days. I imagine he will increase my dosage to
86 units .

I don't understand these higher readings. My diet has not changed
from the low readings taken at 83 units.
For two nights I had Lean Cuisines and last night I had a baked
drumstick and 3/4 cup mashed potatoes. That is what I would eat
at 83 units. The Dr. requests that I send him the readings every
third day. A real mystery!

Have a great day!

I have a question. What kind of insulin are you on??

Are you on the basal insulin (one shot a day).

Which brand???

And are you overweight??

I was classed as prediabetic but treat myself the same as a person with Diabetes 2 would, i don't touch potatoe at all, i love to eat it but it has a terrible affect on my blood sugars, so does white bread.
Instead of potatoe i choose cauliflower and only use very high fibre seeded bread but limit myself to only 2 slices a day.
It's very easy to slip into a diabetic range from a prediabetic state, so the amount and what you you eat is very important, especially if inactive.
My feet were very numb especially on the soles but through tight glucose control and exercise i have regained a lot of feeling back in them.
Good luck
Brian

Thanks to Melodyl and Brian
Yes, I am overweight, I take Lantus insulin once a day. Brian, I am starting
physical therapy at UTSW. Therapist is going to work on my balance and
endurance(exercise). You have given me hope that I can restore my feet.
Thanks again and have a great day!

My opinion is that it imay be a mistake for pre-diabetics to take insulin It may make you dependent on insulin brecause you body may stop making its own insulin because you are getting it externally. Diet and exercise in my opinion is a better solution.

I have been classified as pre-diebetic. My glucose and A1C readings are not too high. I aslo have numbness of the feet but not much pain , only discomfort. I took a class of Tai Chi which has improved my balance. There are also home exercises that you can do to improve your balance. These are the same exercises that you would get if you see a Physical Therapist.

occurs at the tissue level... insulin fails to enable glucose. It doesn't matter if
you inject or use your own.

Research is looking for the causes of the failure at the cell membrane level.
They think it is an inflammatory cytokine made by fat cells.

Studies like you are doing worry me. Instead of sensitizing the insulin you do have to work normally, they just give you MORE insulin?

Metformin, chromium supplements, R-lipoic acid all help insulin work at the cellular level better.

Studies have shown that by the time a person reaches Type II diabetes, 1/2 of their pancreas insulin is gone. I can see using "some" insulin daily when diabetes results, but the dose you are on, is really high for a NON diabetic.

The liver makes more glucose when it senses low blood sugar. That is called gluconeogenesis...and you might be doing that metabolically to account for all that insulin. Drugs like metformin are handy because they shut that down somewhat to lower blood sugar.

I think you should read up on the internet:
topics like this:
Syndrome X (diet suggestions)- Also called metabolic syndrome
Metformin use in insulin resistance

Your health should come first, not some study. That's just my opinion.

Did you work with a therapist to do exercise? I am working with a
therapist with the hope I can get feeling back in my feet. I do
have some feeling but walking on sponges best describes how my
feet feel. I have terrible balance and have fallen twice.

DO not make the numbness go away per se. You have to be very pragmatic and realistic about how nerves are damaged...The nerves can and do die or get damaged very quickly or over a period of time...Healing or regeneration of the nerves is a glacial-like process! No and's if's or but's...ever.
There are three issues going on here?
1- Controlling your pre-diabetes state -meaning you have to change your diet and lifestyle patterns [I HATE that last one!] to put your body in the best position to heal those nerves and give them the 'environment' they need to heal, regenerate or whatever...
2- Physical won't 'cure' you, just help you learn to try and compensate for the damages done and get on with life with more stability. Should nerves and new nerves grow...those nerves are going to need 'direction' thru using them the way they should be used...Repetition of many basic exercises helps give these new nerves [when they happen] the directions they need to be useful in the long term.
3- PATIENCE!!!!! It is a key term for all of us...Taking a vitamin, a med, painkillers isn't going to make the pains of these dead or distrubed nerves go away. Plain and simple. But, they do help you give your body the things it needs best to heal those nerves. I've a more acute type of neuropathy, many many of my nerves died within HOURS! Five years later, after extensive and expensive therapies I might just might be seeing/feeling some improvements. I'm not going to expect things to be 'back to normal' any time soon... Any feeling, good bad or indifferent rite now to me is GOOD...Better feeling than totally NOT feeling [which I have experienced as well] The lack is far far worse than the pains or strangenesses of 'feeling' by far.
Walking on 'sponges' IS a really good description! I've felt like I was walking on bubble wrap, only not having the fun of popping anything.
Hope this helps? 's in the meantime...we all muddle thru somehow... - j