occurs at the tissue level... insulin fails to enable glucose. It doesn't matter if
you inject or use your own.

Research is looking for the causes of the failure at the cell membrane level.
They think it is an inflammatory cytokine made by fat cells.

Studies like you are doing worry me. Instead of sensitizing the insulin you do have to work normally, they just give you MORE insulin?

Metformin, chromium supplements, R-lipoic acid all help insulin work at the cellular level better.

Studies have shown that by the time a person reaches Type II diabetes, 1/2 of their pancreas insulin is gone. I can see using "some" insulin daily when diabetes results, but the dose you are on, is really high for a NON diabetic.

The liver makes more glucose when it senses low blood sugar. That is called gluconeogenesis...and you might be doing that metabolically to account for all that insulin. Drugs like metformin are handy because they shut that down somewhat to lower blood sugar.

I think you should read up on the internet:
topics like this:
Syndrome X (diet suggestions)- Also called metabolic syndrome
Metformin use in insulin resistance

Your health should come first, not some study. That's just my opinion.

That's exactly what I thought when I read on HOW MUCH INSULIN YOU ARE ON and you are not even a diabetic. I know it's very easy for me to tell you to lose weight. I have no idea how old you are or if you can start some kind of exercise routine.

But the facts are, you are not a diabetic, and you are ON LOTS OF INSULIN. You need to teach your body to use the insulin it already makes. At the rate you are going, god knows how much Lantus they are going to give you.

I have been diabetic (type 2) for 20 years. I started with lots of oral meds, I was morbidly obese, and ultimately went into the ACCORD program almost 3 years ago. They started me on 46 units of the Lantus in addition to the 2 Metformin pills I was already on.

Well, I saw a nutritionist, got my act together (it's a whole new way to look at food believe me), but ultimately I lost MOST OF MY WEIGHT.

And the best news is that within a few months I was off the oral meds, and they started to lower my Lantus.

I am presently on 22 units of the Lantus. The only other med I am on is Zestoril for high blood pressure (it helps the kidneys if you are diabetic too).

Really hon, I would see another doctor (an endocrinologist) and run it by him (what you have been taking).

At least think about it. You are on A GREAT DEAL OF INSULIN.

The goal is NOT TO BE ON INSULIN AT ALL, or as little as you need to be.

We're straight shooters on this forum. We only want to help.

I betcha that person wouldn't put himself or any member of his family through what seems to me like a very dangerous experiment trial, there is no way i would let anyone experiment on my long term health, Diabetic complications can be deadly.
The real answer to be extremely careful not to rise your blood sugars above
normal range, be kind to your body and it will eventually thank you, things don't happen overnight but you have a golden opportunity now to loose that prediabetic state, choosing a well balanced diet for your particular needs is very important, a dietitian's help would be useful, ditch any high sugary carbs, its only rubbish that you don't need, eating high fibre low GI foods will release more slowly into your blood stream which will give you the benefit of keeping you fuller for longer and it also takes the strain off your pancreas producing enough insulin.

Brian

Every time I read some thing like that,oh my I'm so glad your here.
Thank you young person,but you full of,never mind we have a right
to our own ,oh never mind. Good Luck,think about what Mrs.d had to
say. Sue

Hi there:

Sorry, I can't be too much help on diabetic advice. Others, who have posted, are far more knowledgeable than I am.

I just wanted to welcome you to our forum and also tell you that I see several docs at UTSW. I live in the area too.

Good luck,
Cathie

I see Dr. Kathleen Wyne who is an Endocrinologist. She is the Dr.
that entered me on this clinical trial.

I appreciate all the input from this forum. I plan to ask her about
all your suggestions.