There are no listed depletions for gabapentin yet.
However some doctors, lump this drug in with other antiseizure
drugs ..but data on that is not available.

The general depletions for anti-seizure medications include
calicum and Vit D. Some of them deplete folate too.

Depakote is the only one I've seen with carnitine listed.
The reference I have states also the family of antivirals used for HIV treatment as affecting carnitine levels.

Some articles do - some just list the majors. You could google: peripheral neuropathy causes and read some articles. Some folks have found that some spreadsheets created by a member here - Liza Jane - are helpful in getting and organizing tests. You can find them and more on her website:
http://lizajane.org/

Finding Clues: Many of us keep pain journals, tracking pain levels, symptoms, meds taken, activities, etc., and over time, we can find some things that help or hinder.
Google: pain journal template for some examples, look them over, then make/customize your own for your particular needs.

We do a lot of our own research as well, reading articles, discussions & threads here, and find some things to try from others' experiences. My philosophy there is, If it can't hurt to try it, then it can't hurt to try it, and to be safe, run it by your doctor first - sometimes a phone call or email will do, and keep him/her informed.

I've found supplements that improved my symptoms enough that I don't need prescriptions for my PN. It's probably best to try one at a time for a month or two rather than taking a "shotgun approach" (starting several at once). If something helps, stick with it. If it doesn't, discontinue (save your money) and try something else. There are certain foods I've found that aggravate my symptoms, so I avoid them. We're all different, and different things/combinations work for each of us.

By keeping a journal (and possibly the charts & spreadsheets) and reviewing them with your doctor, something may surface that leads to your cause (if there is one). Help your doctors help you.

Hope this helps,

Doc

Thank you Mrs. D.

Can I use 2 hours as window between calcium and gabapentin? And 2 hours between fiber supplement and gabapentin?

I would take the fiber with food.

Gabapentin can be taken with some food:
http://www.ncbi.nlm.nih.gov/pubmed/9562133

If you are taking high dose Vit D? I would cut back on calcium to the recommended 600mg a day...that would be one dose.
That should make your schedule easier.

Also I'd do the fiber only once a day too.

I have osteopenia as of last year. Does taking high dosage of Vit D (I assume its Vit. D), will boost my system to make enough calcium to prevent progression? I know this is no longer directly related to neuropathy, but i was just hoping you have some information that you can share with me.

Thank you Mrs. D, as always!

If you are taking high dose Vit D3...the OTC one, it will eventually increase absorption of Calcium from your food, quite a bit.

Some cardiologists are recommending lower calcium supplementation for this reason, to prevent hypercalcemia.

If you eat cheese, drink milk, or eat yogurt, and have veggies like broccoli, and greens, you may not need high dose calcium in supplement form. I cup of yogurt can have 400mg of calcium in it.
Lactaid milk is calcium enriched, and so are some orange juices.

Taking magnesium also improves osteopenia, as well as B12.
There is even a study showing Omega-3s help.

http://www.barleans.com/literature/f...eoporosis.html
Osteopenia is the term for calcium loss in bone in younger patients. But the process is the same.

I drink a lot of milk, but I dont like yogurt. I guess, I need to include yogurt in my diet.

Omega 3 is part of my daily regimen.

thank you.

Thanks Doc!

After my NCV, EMG and Lower Extremity Doppler, my neurologist told me today that I have a Small Fiber Neuropathy.

She suggested that I should have a skin biopsy. My previous bloodworks on antibodies or autoimmune diseases are all negative, but she said that with skin biopsy, there might be some autoimmune or antibodies which can be detected but did not show on my previous bloodworks. Me and my husband were very excited hearing that there is still a chance to find a cause for my painful symptoms.

I hope anybody in the group who have had skin biopsy can share with me their experience/s and the success in finding the culprit, if any.

Thank you.

You mentioned finding supplements that have improved your symptoms for your PN. Would you mind sharing what they are. I know all things do not work for everyone; but find your post quite interesting and really would appreciate your input. For the past few months I have been taking 2mg's of
MethylCobalamin B12, Stabilized R-Lipoic Acid 100 mg, and Best Benfotiamine 150mg's twice a day.

Thanks,
(Ger)