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Old 05-05-2008, 08:51 AM #9
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb What I think happens....

Is that even though Neurontin and Lyrica are similar, they must work slightly differently at the cell membrane level.

People who are on Neurontin for a while, the nerves get "used" to that way, and when you introduce the new Lyrica, either it doesn't get "in" the same, perhaps the Neurontin blocks it, or the nerves just have to "learn" to use the Lyrica
slightly differently. In other words an adjustment period occurs.

These drugs are not identical, and the body tends to "get used to things" and readjust etc. It does this with many other types of drugs too.
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