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Old 03-04-2009, 07:48 AM #1
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This drug has alot of major side effects.

1) Changes in ocular pressure (as Glenn has stated)

2) causes kidney stones in some people

3) causes metabolic acidosis in up to 30% using it.

So you need careful monitoring, frequent eye exams,
and blood tests for serum bicarbonate.
Some doctors do NOT monitor patients closely enough when
ordering this drug. So keep that in mind.
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Old 03-04-2009, 08:44 AM #2
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It caused me to lose my short term memory for 3 months while taking it.
I couldn't remember anything and was in a brain fog like a bad dream.
Once off it, everything came back to 'normal'. It did not help my pain or Sx from PN. I never got to titrate up to the dose my doc was aiming for (400mg/day).
It should be titrated slowly in 25mg increments over a long period of time. I didn't like it. It did cause me to lose 5-10 lbs over 3 mos, though.
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Old 03-04-2009, 10:09 AM #3
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Quote:
Originally Posted by nide44 View Post
It caused me to lose my short term memory for 3 months while taking it.
I couldn't remember anything and was in a brain fog like a bad dream.
Once off it, everything came back to 'normal'. It did not help my pain or Sx from PN. I never got to titrate up to the dose my doc was aiming for (400mg/day).
It should be titrated slowly in 25mg increments over a long period of time. I didn't like it. It did cause me to lose 5-10 lbs over 3 mos, though.
Yes... this drug has been called "Dopamax"
I think it is part of the acidosis aspect of it.
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Old 03-04-2009, 10:15 AM #4
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My DD is on Topamax for severe migraines and it has helped her so much. Her Neuro is going to wean her off of it soon, so he says.
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Old 03-04-2009, 12:39 PM #5
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Thanks a lot everyone. I do have glaucoma, somethng that my neurologist may have overlooked. I'll address this with him.
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Old 03-04-2009, 06:18 PM #6
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Quote:
Thanks a lot everyone. I do have glaucoma, somethng that my neurologist may have overlooked. I'll address this with him.
I would go directly to my eye doctor, not the neuro. I work for an optometrist, and as soon as he found out I was on Topamax, he put me in the chair and checked my eyes.

I was on Topamax for nearly a year, with no results. My neuro at the time kept increasing the dose, thinking it would stop my headaches...never happened. I also did not lose weight on it, although it does curb your hunger, after going off it, I was very hungry for months, it seemed.
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We urge all doctors to take time to listen to your patients.. don't "isolate" symptoms but look at the whole spectrum. If a patient tells you s/he feels as if s/he's falling apart and "nothing seems to be working properly", chances are s/he's right!
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