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Old 10-31-2012, 10:22 AM #1
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Some statins are more lipophilic (soluble in fat) than others.

Simvastatin is one of those. But all statins, are implicated in the side effects profiles. Simvastatin was chosen for the early trials for MSers, with the thought it would enter the brain, and help there. This was totally a failure, and the studies were stopped.

All statins block the enzyme in the liver that makes CoQ-10.

It is your choice. But if you don't stop the statin you will never know if your PN is because of it.

Given the tiny percentages of benefit that are now being quoted for them, I don't see people remaining on them once the push from the drug reps ends. Almost everything doctors and patients know about these drugs was Big Pharma driven until just recently.
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Old 11-02-2012, 02:28 PM #2
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Quote:
Originally Posted by moaningminnie View Post
When researching information on peripheral neuropathy I found this information:

“For susceptible individuals, the use of a statin drug can interfere with proper functioning of peripheral nerves. Researchers assume that the build-up of statins in the body causes neuropathy in some individuals. If left undiagnosed, neuropathy can lead to deterioration of the muscles and paralysis. This can lead to problems swallowing, breathing, and complications of the heart – as these all involve muscle groups. In the extreme case, severe neuropathy as a side-effect to statin use can lead to death.”

I took Lipitor/statins for two years and suffered a life-threatening adverse drug reaction last year. I was told to stop the drug after a blood test showed my cholesterol level had gone down dangerously low to 4.mmol/L. I first reported a horrendous pain and pricking sensations in the upper back, could hardly talk, felt 'nervy' and had difficulty writing. I checked these symptoms on the internet and found 'statins and ALS-like syndrome' which fitted my symptoms. But I now believe these symptoms are autonomic and peripheral neuropathies caused by the statin drug which are very similar to the 'ALS-like syndrome' description. So perhaps the label 'ALS-like syndrome' is wrong and the correct diagnosis is actually peripheral neuropathy. There is an on-line petition to the pharmaceutical companies from hundreds of people who have suffered peripheral neuropathy caused by Lipitor/statins. Dr Ralph Edwards, Director of the Drug Monitoring Centre of the World Health Organisation has been carrying out research on hundreds of serious reported cases of 'ALS-like syndrome' caused by statins but I believe the correct diagnosis is peripheral neuropathy - a very frightening, disabling disease caused by many other drugs as well. I almost died of cardiomyopathy and neuropathy as a result of the statin-induced toxic/chemical poisoning but was never admitted to hospital/intensive care for investigations and treatment and have been left with irreversible damage. The GPs and hospital doctors concerned are in denial refusing to admit that the statins have done this and have refused proper investigations and treatment that could have reversed the damage. I read my medical records recently and discovered record tampering to cover-up the medical disaster and have been struck off two GPs registers because of it. In the referral letters they said I was on the drug for three months (to deliberately mislead) when I was on it for two years. The GP who prescribed the statins refused to report the emergency ADR to the MHRA so their statistics are grossly unreliable. I was housebound and extremely ill for four months and on a home visit the GP refused to authorise an ambulance to take me to hospital. I have reported the malpractice and sub-standard healthcare to the appropriate health authorities. I have read about adult stem cell treatment that may be able to treat the muscle wasting and blood vessel damage which seems to be the only hope of a possible cure? One clinic said they hear many statin horror stories like mine and have treated patients successfully with these conditions. Lipitor/statins is an extremely dangerous drug and Pfizer should be forced to withdraw it from the market immediately. It is a fraud and those responsible are putting profit/greed before patient safety. Statins don't save lives - it severely harms and kills thousands of patients around the world. It is a 'disease' invented by the pharmaceutical companies and the medical establishment is in cahoots with this money spinning sham. I never had any heart problems before I took statins and it has been a horrific experience. It's a terrible state of affairs, and very scary indeed, when I can't trust my own doctors now to tell me the truth and care for me. No wonder people who've been on statins have suicidal thoughts.
My story is almost like yours,but not quite so severe, my Dr."dosen't know what is causing the neuropthy,but dosen't believe it is statin related" They are all in the drug companies' pocket.
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