--but Rose and Mrs. D have reported about nitrous oxide depleting B12 in susceptible people and leading to neurological symptoms:

http://psychology.wikia.com/wiki/Nitrous_oxide

http://www.umm.edu/altmed/drugs/nitr...ide-091811.htm

http://www.ncbi.nlm.nih.gov/pubmed/8250714

http://www.ncbi.nlm.nih.gov/pubmed/8...ubmed_RVDocSum

http://jama.ama-assn.org/cgi/content...ct/255/12/1605

http://journals.lww.com/anesthesiolo...&type=fulltext

There's considerably more available through PubMed and Google Scholar, but you get the idea--it's definitely an area of concern.

Repeated usage of nitrous oxide for a person with CMT is not recommended. It can make it worse.

This is something I would have suspected in chronic abusers or people requiring many anesthetizations - but not from single/brief instances as I'm inferring from the links.

If this is the case, wouldn't it be so simple (and prudent) to follow up nitrous anesthetization with a B-12 shot as S.O.P.? (rhetorical)

Doc

There IS a caution in those detailed 'prescribing information sheets' for those meds about not taking these meds the day of the procedures? And, as a result? I've got a BIG 'NO epinepherine' note on the front of my dental file!
The descretionary use and cautious use of many anathestics for PN'ers is similar to a degree with those who have MS. MS Folks have and are the lead in the forefront about how many painkillers can make the long term pains worse.
I'd consult 'jointly' [?] with Bryanna from the dental forum http://neurotalk.psychcentral.com/forum89.html And what Mrs D advises.
A really Good to Great dentist and good dental care are keys to saving your teeth IF YOU CAN!
's!!!! - j

I believe in people who are borderline low in B12...one snootful of Nitrous can have consequences. People with very good levels or high maybe not. The latter may react with repeated exposures.

This link discusses those people with the MTHFR mutation, faring poorly after nitrous.

Not good for children:
http://www.ncbi.nlm.nih.gov/pubmed/17683399

Alot depends on the medical status of the person receiving it.

My daughter received nitrous oxide when she was in high school. We had a 2 hour drive home and it was entertaining to say the least.

What concerns me is she didn't clear it.

First of all, she was laughing and behaving in such a 'funny' manner, the dentist made us leave thru the back door. She got into the car seat upside down. I thought she was kidding....she wasn't. The most bizzaire conversations and behavior continued for 2 hours all the way home, then when she came out of the 'funnies', she was not feeling well at all.

She has autonomic issues now, not as bad as mine, but she is of course, much younger. She has not been tested for PN.

I had general surgery where the sucinyl choline took and what ever they use to knock people out did not. Needless to say, I was aware. (This was the C-section for the above mentioned daughter). Awful experience....and this was before they knew of anesthesia awareness.

I had an ablation a decade ago (I regret it) and they did a general....I was not aware but when I awoke, they could not stabilize my vital signs, basically it looked like hypovolemic shock, but it wasn't. My BP and P would not go up, into the normal range, and after this experience, I have never been 'normal'. I told them I felt like I had a 'stroke' like episode, but it is dysautonomia, I guess. I am fearful if I ever need a surgery that requires a general, I will be up the creek.

I have the most local or regional anesthesia I can. I also have a 'NO EPI' on my chart.

Besides PN, and other than CMT are there any metabolic conditions, mitochondrial myopathy like things that cause this?

I work in the dental field and have not heard of local anesthetics causing any type of neuropathy. The most common type of local anesthetic used now is called Septocaine. But, some people can get a rare numbness from oral surgery due to damaged nerves during the surgery. Most cases take 3-12 months before the nerves heal back to normal.

Now, general anesthesia is different. I had an epidural and spinal block 5 years ago for me c-section and I have been sick ever since then. Body pains, fatigue, headaches. I know that it was the anesthesia that caused it. After my surgery, I was shaking so bad from the anesthesia I couldn't hold my son for the first 3 hours of his life. But of course Dr.'s never think the two could be related. Now my pain Dr. wants me to consider Ketamine infusions. I'm not sure that I want to do that considering the bad reaction to the anesthesia last time I had it!

for others it's the COMBO's of some of your meds, epinepherine AND your condition.
I do know that MS folks are far more aware of these interactions than most people are tho...I don't know all the hows or whys of it all? I just know that most circumstances have been well documented [and...I'd learned this all over 5 years ago?].
Only thing to do for now? Is to find out what 'good stuff' they used? Then try to avoid it in the future....there likely is other 'good stuff' available that can work as well yet not add to problems. Tho some of the anathetics my dentist uses now are shorter lasting..but? They have to work more quickly, so... I'm not sitting in that chair soo long! Plusses and minuses to each and every thing, I guess.
Especially important IF you've autonomic issues to NOT aggravate them any more than possible. Bad enuf as it is! NO?
Good luck! 's !! - j

really?people may have neuropathic result after any dental procedures?
actually i am afraid of removing my teeth. i always think of what is the best thing to be done that is free from pain.

Hello Sephchu, I want to welcome you to Neuro Talk. There is also a good dental forum on this site. Use the search bar up at the top of the page if you would like to. You have found a very compassionate site, and many people will be able to say hello and address your concerns.
The most knowledgeable that I have met here is Bryanna. She has some wonderful insites on dental issues.
I have had a reaction to nerve blocks in particular. I got alot of tingling, shocky feelings for quite awhile after the proceedure. The last time I had a tooth removed last week, I was put to sleep, but still had the shot and didn't get a reaction. I am not sure why there was a difference in the two injections and their reactions. Keep posting, and someone may be able to address your concerns. I am sincerely hoping I don't have to go back for another dental visit for awhile ginnie