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Old 08-12-2009, 06:21 AM #2
glenntaj glenntaj is offline
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glenntaj glenntaj is offline
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Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default This does sound--

--like some molecular-mimicry autoimmune process, and it may very well be related to gluten sensitivity. That isolated anti-gliadin finding is often found in those whose gluten problems present neurologically, rather than gastrically (that anti-transglutaminase level is more correlated with degree of villous atrophy in frank celiac), as Dr. Hadjivassiliou has researched (you can find out a lot about this in The Gluten File: http://jccglutenfree.googlepages.com/).

Such people often have subclinical malabsorption issues that may lead to neurological symptoms as well--you should have your B- and D-vitamin levels checked, especially B12, B1, and B6, and mineral levels looked at.

Avoidance of gluten may enable the gut to start healing over time, and may help with neurological symptoms as both malabsorption and direct effects of gluten on neural epitoptes recede, but this may take a very long time. (Nerve healing in general is very slow). One may also find that one has multuiple sensitivities and may need to examine other foods (caesin is a freqeunt co-culprit) to get a full recovery effect. Even then, a number of people have reported that they have just arrested the neuroplogical progression rather than reversing it--inddividual results vary widely. People with zonulin dysregulation--zonulin regulates the cellular spacing in the gut, mediating what kinds/how many pathogens may pass through into the body for possible reaction--seem to have the most difficulty (the greater the dysregulation, the more likely that things will escape the gut and be reacted to, and the more likely one of these will start an autoimmune reaction through molecular similarity to some kind of body tissue).

I think you have to be REALLY strict about not eating gluten, and experiment with other food elimination. It might behoove you to revert to a very paleo-type diet--fruit, vegetables, nuts you're not allergic to, lean meats, minimal processed food--and see how that goes.

Last edited by glenntaj; 08-12-2009 at 10:12 AM.
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