I see that I must make a correction to my post above.

I had been taking 5 grams per day with little or no result. Then, I upped the dose to 50 grams per day with very good result.

mrsD, I'll have to track down your d-ribose thread and review it again, and do more research on side effects of d-ribose. I don't have diabetes or blood sugar issues (yet), and I would hate to have to give up this supplement and lose its effects, as it has made all the difference for me.

Thanks, as usual, for your great information and circumspect advice!

Well if 50 grams works for you, then maybe you really need it that high.

I don't feel comfortable with that high dose, because of that link, and also because high use of ribose may increase uric acid in the blood, and cause gout. This was mentioned in that link too, and also in this one:

http://chronicallyme.wordpress.com/2...make-you-sick/

Gout is very sneaky. In fact I think my ankle which has been bothering me alot for months may be gout, because of the reduced blood flow I have in it from the previous surgery.
My doctor agrees, and I have a slip for blood work, which I will take in next week to the hospital for testing.
You can have high levels of uric acid and no gout attacks, for a long time and boom... then you get one. So increasing uric acid in people with this tendency (some drugs like diuretics cause it too) is really not safe here either.

At the doses I used, I found a steady slow improvement with time. Perhaps taking more will give faster results, but once you are up there where you want to be, I'd consider slowing down on the ribose some, to a steady state lower maintenance amount. There are no studies on chronic use...but I suspect the systems get saturated over time, and the high amount may no longer be necessary. (unless you are building new muscle at a fast rate).

Keep in mind I don't have blood work on people here in front of me like a doctor would, to guide advice. I give conservative advice, and let the readers decide for themselves. That means it becomes YOUR responsibility to choose whether to take something and how much. Many people tolerate high doses of things that others can't. It is really impossible on the net to predict who is who.

I do think you understand that.

Hello,

My husband was diagnosed with Parkinson's Disease in January 2011. He initially started taking azilect, but quit taking the drug due to the long-term side effects. He is now doing a number of things to address the disease, e.g. vegan diet, chi kung, alexander technique, running, etc. A friend has recommended the Neuropathy Support Formula that has been discussed previously on this blog. What do you think?

It cannot hurt. But realize that unless you get testing, you won't know if B12 is an issue for you.

The Benfotiamine in it is also useful, but no in every patient with PN.

This supplement tends to cost more than buying the ingredients separately.

More discussion on R-lipoic acid:

http://neurotalk.psychcentral.com/thread159210.html

We all can always learn something new...and this thread illustrates THAT!

Another thread with discussion of R-lipoic acid stabilized:
http://neurotalk.psychcentral.com/thread130991.html

I just finished skimming this thread for mention of Vit-C. I didn't see much, and those who said they take it, don't take much, e.g., one person said they only take 500 mg.

The reason I ask is because I just got bloodwork done on Thursday, and the company which does it has a flyer listing all the Nutrients, along with how common the deficiency is, plus "What It Does."

Vitamin C:

Is that a typo?

What are therapeutic doses of Vitamin C?

I usually take 1,000mg to 1,500mg/day. One time I took about 7,500mg.

Most of the talk about Vit-C I've seen is about its immune system help and antioxidant value, not its mitochondrial support or nerve system support value.

I take 500mg a day Ester C.

Vitamin C is showing promise in RSD... as an antioxidant, to prevent spread and help control it. Some studies done on surgical patients in UK showed it prevented RSD in fact in about 1/3 or so.

Coenzyme Q10 (CoQ10) is present primarily in the mitochondria.

In a thread on this site, it has been suggested that "damaged mitochondria are at the heart of many forms of [Peripheral Neuropathy]."

CoQ10 generates energy in the form of ATP. "Muscle and nerve cells are big users of ATP."

Statins are known to cause peripheral neuropathy and they are also believed to lower CoQ10.

CoQ10 functions in every cell of the body to synthesize energy, and supplementation can help heart, brain, gums, etc.

It is fat-soluble and best taken with meals containing fat. Some have advised to take it with the fattiest meal of the day for maximum absorption.

"Synthesizing CoQ10 is a complex, 17-step process that requires multiple vitamins and enzymes," according to Ross Pelton.

Recommended dosages range from 30 mg to 300 mg or higher.

"CoQ10 has an excellent safety record."

Related Article: Bioavailability of CoQ10 by Dimitri Papadimitriou, Ph.D.

Hi all, new member, my neurologist diagnosed me recently with idiopathic PN and has me on Neurontin for the past few weeks, which seems to help a bit. I have a second visit in a few days and expect he may increase the dosage, I'm not having any problems with being groggy.

I have spent a bit of time searching this forum and see very little on the subject of an over-the-counter supplement called Neuropathy Support Formula. They are advertising VERY heavily and I see them as ads all over the Internet. The ingredients are a blend of a number of the B vitamins and other supplements discussed in this forum.

Has the group addressed this product, and if so, can someone please point me to the right thread? I have printed a copy of their ad and plan to take it to my neurologist at the upcoming appointment and get his opinion.

Welcome to NeuroTalk:

We have several posts on this subject.
This product will only help those who need these nutrients.
The advertising implies EVERYONE needs them, and that is just not true.

Have you had B12 testing? Do you know the numerical result?
If you use the search function here, you'll find several threads.

This product will not be harmful in the long run, except to your wallet. So if you want to try, go right ahead. But I think it is best to know where you are, and if you have deficiencies that this will address.

The Benfotiamine may work if you have diabetes, drink alot or have a B1 problem. The ALA in it is the old version that is not well absorbed-- it needs empty stomach use. The methylB12 in it, requires you take it on an empty stomach. That is about it. The rest of it just duplicates
a multivitamin.