Welcome to NeuroTalk.

For some things there are no rules, for others, there are some, but they are few.

List what you take and I will try and help you figure it out.

I have a similar question I have NP and I began taking the methyl b12 1000 but just order the 5000 , I'm also taking benfotaimine 600gm a day and today I began taking complex b with folic acid and vitamin c(all in one by natures best) I was taking centrum womens but stopped. I have read most comments but im still unsure if I should take and how much I should take of zinc , biotin, coq10 , rlipoic , magnesium , fish oil, acetyl l carnitine and vitamin d I also read that acetyl l should be taken with ALA but I read rlipoic is better than Ala .I would really like some help since the numbness and tingling returned to my foot after a year and now I began feeling needles in my hands !! Thanks in advance

Thank you so much for your help! Currently I am taking Lovazza and Niaspan for something else along with a 325mg aspirin.

I also take Metanx which is a B complex (i think) I was going for B12 injections but the new doctor (mine retired) is an *** and won't give them to me. Even though I told him I was told by a specialist that once deficient always deficient.

Is this a good one or should I switch to over the counter? I know that you are all not doctors and therefore can not prescribe but the pain is overwhelming and I have been this way for almost 15 yrs. I have been to specialist and none have figured out the cause or done anything but push the pills,which I might add only made me very sick.

Sorry for the rant... anyway I have been doing a lot of reading about supplements that will help. I will be trying RLA and Serrapeptase and D, are there any others that might be helpful? Thanks

Most vitamins can be taken with food.

Exceptions.

1) Separate B12 oral should be on an empty stomach.

2) Lipoic acid is absorbed better on an empty stomach.

3) acetyl carnitine is best broken up into several doses and not taken all at once in one large dose.

4) Products in oils, are best taken with food.

5) calcium supplements are best taken in divided doses too.

I think you should get tested for Vit D and B12 to see where you are presently. This would then point to how much you need if you really need them. Zinc can be tested for too.
Zinc is unlikely to be low unless you take ACE inhibitors for blood pressure, or daily acid blocking drugs. Prednisone and birth control pills may lower zinc levels too. People eating meat, and seafood, do not get low in zinc as a rule.

Choice of which supplements to start on and concentrate on depend on your medical history. What is causing your PN?
Trauma/injury? at a young age? Type I diabetes? Hereditary? Supplements may not work on hereditary patients. Heavy use of therapeutic agents that damage nerves...chemo and other drugs? Lupus?

If you have a basic nutrient deficient PN from low B12, the other supplements are less important, than fixing the B12 first.
If you add too many together in the beginning you cannot see which of them are working and which are not.
Since magnesium is needed and commonly low, taking a good
product (not OXIDE type), at 1/2 the RDA is helpful. Many people in US are low in magnesium...not just diabetics and PNers.

The B-complex, C, and magnesium are useful for many people other than PNers. It all depends on what your diet is like, and your medical history, and drugs being taken, OTC and RX.

Thank you so much for your help! Currently I am taking Lovazza and Niaspan for something else along with a 325mg aspirin.

I also take Metanx which is a B complex (i think) I was going for B12 injections but the new doctor (mine retired) is an *** and won't give them to me. Even though I told him I was told by a specialist that once deficient always deficient.

Is this a good one or should I switch to over the counter? I know that you are all not doctors and therefore can not prescribe but the pain is overwhelming and I have been this way for almost 15 yrs. I have been to specialist and none have figured out the cause or done anything but push the pills,which I might add only made me very sick.

Sorry for the rant... anyway I have been doing a lot of reading about supplements that will help. I will be trying R Lipoic and Serrapeptase, are there any others that might be helpful? Thanks

The Metanx is good, but it needs to be taken on an empty stomach so the methylB12 in it can be absorbed properly.
No food for one hour.

The Lovaza is fish oil...take with food.

The R-lipoic acid (stabilized) is very water soluble, but still should be taken on an empty stomach for best results. This newest version is an improvement over others from the past.

I will have to warn you that 15yrs of vitamin deficiency may not be helped much. There may be damage that is not correctable.
If you are lucky and start to improve, it will be a long haul.

Do you know your A1C numbers, the long term diabetic predicting values? Do you know what started you problems?
An injury, illness, treatment of some kind, some vaccine reaction, etc? This information is helpful to help decide which supplements to concentrate on.

I am not Diabetic and the so called doctors are not interested in finding out the cause so it has been hit and miss for me. What I am looking for is releif from the agonizing pain There has been no injury to account for this or so I am told....

I have been told that my body is very inflamed and I have had a LEAP done and am apparently sensitive to many foods.

So the Lovaza should help. And the aspirin.

Get the tests if possible. If you cannot get the Vit D done, keep at 2000IU of D3 daily only.

If you suspect leaky gut, food etc intolerances, I'd try Kefir too.

This is 12 probiotics , and gluten free. I hope you can tolerate dairy? It is wonderful for reducing problems from the GI tract and inflammation there.

http://www.lifeway.net/

I have found this very helpful for myself!

So the Lovaza should help. And the aspirin.

I have been tested for D and it s an 18 the dr was giving me a supp then told me he would not longer.... I am working on the leaky gut via an alkalizing diet as I and addicted to sugar...What is Kefir? I started juicing for nutrients but with my hands it is hard

I can tolerate dairy but it seems to make the pain worse and I have read it is bad for you...

Kefir is fermented milk. It is thinner than yogurt and better. It is very healing with many probiotic organisms in it which settle the GI tract and allow for healing.

Check out the link. We get ours from Kroger's.

The OTC D3 works far better than the RX D2...so you don't need the
doctor's RX at all...it doesn't really work.

The general rule is 1000IU D3 daily for every 10 pts need to raise.

So you could take 3,000 to 4,000IU daily, to get in a more normal range.