I take 250mg of the Mega Benfotiamine by Life Extension. It was added to my ALA and other supplements a couple of months ago. The rate of nerve healing went way up. My feet are almost healed now.

My Autonomic neuropathy was only noticed in my feet as far as what I could feel but with my POTS, it is all over of course. My OI (POTS) is so much better now also. It is very exciting. I am thankful for supplements that heal.

I just added this study to my Benfotiamine link:

This fat soluble form of Thiamine is far better absorbed than regular Thiamine. The old dose of thiamine for PN was 300mg a day or less. This is before gabapentin hit the shelves!

Because it is so much more absorbed, and because it stays around LONGER...not excreted so quickly... I have qualms about such high doses. I searched PubMed recently and there are no papers to speak of for this nutrient on dosing. I found ONE paper for cardiac damage indicating 400mg a day in a small subset of patients. I found only 2 pgs on PubMed, and those were mostly in animals, and from other countries.

So I will remind people here, that the high 600mg or more dose a day... comes from sites that sell this. For that reason, I personally cannot endorse it at those levels or beyond.

But since this is OTC...you can do what you choose, based on what you learn about it. If you decide to do this very high dose, just be very vigilant. It may be that only weeks are needed for this way. There is no evidence that really LONG term use, is safe yet, or that effective for most people.

I, myself, take 150mg a day. This keeps me from severe burning.
I also drink moderately 2 or 3 times a week, depending.

That's remarkable. I am so happy for you that you got such a good result!

And thanks for sharing this info!

Thank you. When I said all over, the Autonomic Neuropathy affects the blood vessels (OI) heart etc, but the place I can feel it is my feet. I responded great to all of my supplements, but the ALA and especially the have been healing for me.