I think it is VERY revealing that people never remain here and become productive members, sharing their experiences etc, and spending time with us, who ask this question.

We are very familiar with "shotgun" combination remedies or various other remedies that target PN that have considerable flaws... EVERYONE is different and a one fix for all just does not exist.

It is best to understand YOUR own PN... before starting any supplement regimen.

Revealing of what, exactly?

Doc

--that some of the people who ask questions like that are actually stealth marketers. (Don't know if that is exactly what Mrs. D is referring to, but there seems to be a sense of "why aren't you guys talking about this" to a lot of those kinds of posts.)

Also, be aware there are two very similar sounding
products:

Neuropathy Support Formula
Nerve Support Formula

If it sounds too good to be true...well, that is your answer.

This list of ingredients and their cost if purchased separately
at the end of Neuropathy Support Formula's website is laughable.
It is exaggerated to make their expensive version look good.

That is not to say individually some of the ingredients may work or not for some people here. But it is important to understand your own body, get testing for B12 and Vit D at least (and B1 and B6 also if you want) before buying an expensive product.
We have had people here that tested low in B6 and B1. That is not as common as B12 and Vit D problems, however.

I just went to their website again... The Neuropathy Support formula:

They have changed their ingredients...the labels now read:
R-lipoic stablized instead of ALA.

I had a breakdown on the forums somewhere about their pricing claims...now I can't find it.

Suffice it to say, 5mg methylB12 oral costs around $4.00 a month from Puritan's Pride. (a brand I tested out as effective with blood tests, when it was newly offered.).-- not $13.34 as appears on that site.

Vit D3 5,000 IU daily -- at Puritan's 100 caps at about $4.00 or
4 cents a cap. Depending on their sales at the time you order.

I would say the herbs are useless...ignore those. Tiny amounts and not detailed as to size of each listed either. This is a common trick to look good... many supplements do this to impress potential customers.

Benfotiamine by Doctor's Best (a high quality company) at Amazon is $13.80/120...so at a day (600mg), a month's supply would be $13.80 and not $50 as claimed.

I suspect the R-lipoic was changed on the site, but its dose was not.
300mg a day of that is rather too much IMO. Its price on the list also reflects the old ALA... so I have to wonder if the labeling is correct or if the R form is even in the product. Not a good thing.

I am not going to do any further, because this illustrates enough how the website is deceptive.

So the bottom line is: If you have the money and think or know your PN is vitamin deficiency driven, you can decide whether you want to try it. But don't expect big improvements... as you may see some or none at all. (depending on whether you need this formula). 4 capsules a day puts you at 300mg of r-lipoic acid based on this label, and this may be too much for some people. Diabetics should montior blood glucose. Long term use of high dose lipoic acid may reduce the absorption of Biotin, and over time this may become apparent with side effects. Studies are still ongoing with this interaction.
And take it on an empty stomach for best absorption.

And ask for testing at your doctor's office since you are going there soon.

OT: Before going to my doctor next week, I am putting together a list of things I want him to test for. Can he test for levels of Biotin?

Yes, there is a urine test I believe. But you know, the reports on PubMed that I found for the two patients with loss of taste,
tested NORMAL on biotin and the doctors gave high doses anyway and they improved.

So the actual Biotin understanding remains murky. I don't think it is worth testing for, if the tests don't reflect biological resistance to it.

Here is a nice WebMD explanation, stating testing is not accurate.
http://www.webmd.com/vitamins-supple...entName=BIOTIN

I've been thinking about this quite a bit.... it could be some people here are marginal on biotin activity and that is contributing to their PN symptoms. It appears that biotin is very safe and inexpensive and worth a try. It would have to be high dose, and taken away from any lipoic acid or high dose B-complex because of the B5 content.

I just received my 5mg from my yearly Puritan's purchase. And I just increased to 10mg at night after 5 days of 5mg.