Gabapentin, Synthroid and Nortriptyline

Idiopathic PN · 05-28-2012, 07:07 PM

I dont think Dupuytren's Contracture is what I have. I have had hand x-ray before and it showed osteoarthritis with spurring.

Thank you for the link Mrs.D.

Its a waste to stop the SAM-e because my husband bought several boxes of 200mg. Oh well.....

I tried Tiger Balm, Icy Hot Cream/Gel.... I tried Salonpas pacthes for my back but not for my fingers.

Actually, I thought of soaking my fingers in Epsom but for now I only soak my feet on a daily basis. You think it will help?

Quote:

Originally Posted by mrsD

Have you tried topical things for your finger swelling?

Salonpas patches OTC may help. The original ones can be cut to size to fit over fingers.

Have you soaked that hand in epsom salts?

If the SAMe is making you anxious, you may not need it.
Side effects are more common in people who already have enough SAM being made in their bodies.

I am also wondering about that finger...
Is this what you have?
http://www.orthogate.org/patient-edu...ntracture.html

Have you seen a hand specialist at all?

mrsD · 05-29-2012, 12:05 AM

Try the SAMe every other day. Spacing it out sometimes reduces side effects if they are present.

Yes, try the epsom salts...it will relieve any muscle/tendon
contractions.

The original Salonpas in the little envelopes can be cut into strips.
I've used them that way many times...mostly on my big toes.
Keep them in a ziploc baggie after opening, to keep fresh.

http://www.drugstore.com/salonpas-pa...9?catid=183102
read the labels carefully to make sure the methyl salicyclate is in them.

You don't have to put right on the joint, but right next to it on either side. It will diffuse to the joint area too.

felix happy · 12-16-2013, 08:31 PM

am on gabapentine alone. Have been for years. Current dose is 300mg 2 times daily and 600mg at night.TER

Quote:

Originally Posted by Idiopathic PN

As you may have read my previous posts, I am on Gabapentin and Synthroid.

I had my follow-up consultation today with the neurologist who did the skin biopsy. I did not want to expect too much today but you must understand that in my heart, I was hoping that he would say something encouraging or worth pursuing.

Well, it was a let down, he just emphasized the negative result of my skin biopsy and he did not want to pursue any further tests. He said that whether my result was normal or abnormal, I will still hve to treat my symptoms.

He gave me another medicine - Nortriptyline. I know this is an anti-depressant medicine. This is supposed to be taken as complementary to the Gabapentin.

I am so hesitant to take this combination because of adverse side-effects. As it is, Gabapentine alone makes me so drowsy and sleepy. To add Nortriptyline will maybe makes me a zombie

.

To add to all this, I have my unstable thyroid function. My last thyroid result was normal after 6 months of being low, but even then, the normal was still "below normal" level. And I read that Nortriptyline may result to exogenous thyroid.

I am stressed because I found out today that the Gabapentin and the Synthroid
I am taking all this time are with Gluten. I have been on gluten-free diet for a month now and yet all this time, I am ingesting gluten!!!

Does anyone have (had) a good experience with the combination of Gabapentin and Nortriptyline? Or is it better to be taken only either one of them. I was given with the lowest dosage for Nortriptyline. Doctor said that if the combination works, we will slowly taper down the Gabapentin.

Will appreciate your inputs.

Idiopathic PN · 12-16-2013, 09:56 PM

Quote:

Originally Posted by mrsD

Have you tried topical things for your finger swelling?

Salonpas patches OTC may help. The original ones can be cut to size to fit over fingers.

Have you soaked that hand in epsom salts?

If the SAMe is making you anxious, you may not need it.
Side effects are more common in people who already have enough SAM being made in their bodies.

I am also wondering about that finger...
Is this what you have?
http://www.orthogate.org/patient-edu...ntracture.html

Have you seen a hand specialist at all?

I am having some flare up of my osteoarthritis in my fingers. Some knuckles are tender, swelling and of course painful. I put salonpas in my fingers. It helps. (Salonpas is getting expensive too!)

Mrs.D, I started taking SAM-e again since 2 months ago. I dont notice anything with my osteoarthritis but i think it helps my mood. My health conditions have started giving me so much fears and anxieties. With continuous use of Sam-e, the feelings of being scared and anxiousness have lessened. I still have some and how I wish I could overcome these feelings completely. I take 400mg a day.

Thank you.

Mary

mercer45 · 12-17-2013, 01:20 AM

mrs d.have you tried topamax for idiopathic PN? Mine turned out to be from a type of bromide/biomene/cleaner keep at very high level in my spa. I did not know for 18 years. it's a long story.....topamax has side effects[looking for nouns +a special type of memory effect] my dosage i 50mg ,three times a day.reduces pain50% +opoids.mine is feet to waist.Dr. gives slowly....PN ruined my life .nerologist,I saw 4 .bye mercer45

Libby100 · 01-20-2014, 11:13 AM

Quote:

Originally Posted by Idiopathic PN

As you may have read my previous posts, I am on Gabapentin and Synthroid.

I had my follow-up consultation today with the neurologist who did the skin biopsy. I did not want to expect too much today but you must understand that in my heart, I was hoping that he would say something encouraging or worth pursuing.

Well, it was a let down, he just emphasized the negative result of my skin biopsy and he did not want to pursue any further tests. He said that whether my result was normal or abnormal, I will still hve to treat my symptoms.

He gave me another medicine - Nortriptyline. I know this is an anti-depressant medicine. This is supposed to be taken as complementary to the Gabapentin.

I am so hesitant to take this combination because of adverse side-effects. As it is, Gabapentine alone makes me so drowsy and sleepy. To add Nortriptyline will maybe makes me a zombie

.

To add to all this, I have my unstable thyroid function. My last thyroid result was normal after 6 months of being low, but even then, the normal was still "below normal" level. And I read that Nortriptyline may result to exogenous thyroid.

I am stressed because I found out today that the Gabapentin and the Synthroid
I am taking all this time are with Gluten. I have been on gluten-free diet for a month now and yet all this time, I am ingesting gluten!!!

Does anyone have (had) a good experience with the combination of Gabapentin and Nortriptyline? Or is it better to be taken only either one of them. I was given with the lowest dosage for Nortriptyline. Doctor said that if the combination works, we will slowly taper down the Gabapentin.

Will appreciate your inputs.

Ok, need to know if you are taking the generic form of Synthroid? there is a big difference between the generic and the name brand, cost difference is that great. Generic has more side effects, and does not work as well, or come in as many strengths as the name brand. I'm Hypo Thyroid. And had been under treated for years. SEE an ENDO not your PCP for treatment. Your Thyroid is the master gland in your body and controls all other glands.

Had to get off mine for 2 weeks for a ENT test, and the joint and muscle pain was out the roof in 2 days.

As to the Gabapentin or lyrica about the same drug, I react badly to them. Could be some genetic to as my elder son has the same reactions for his PN.

ger715 · 01-20-2014, 12:28 PM

Quote:

Originally Posted by Libby100

Ok, need to know if you are taking the generic form of Synthroid? there is a big difference between the generic and the name brand, cost difference is that great. Generic has more side effects, and does not work as well, or come in as many strengths as the name brand. I'm Hypo Thyroid. And had been under treated for years. SEE an ENDO not your PCP for treatment. Your Thyroid is the master gland in your body and controls all other glands.

Had to get off mine for 2 weeks for a ENT test, and the joint and muscle pain was out the roof in 2 days.

As to the Gabapentin or lyrica about the same drug, I react badly to them. Could be some genetic to as my elder son has the same reactions for his PN.

There most definitely is a difference between the generic and the brand name Synthroid.

My endocrinologist originally had me on the generic. He has me get a blood test every 4 to 5 months for throid. Eventually, he said I needed to get my medication for my throid increased. I informed the doctor I had read that the generic for Synthroid should never be used. There is quite a difference.

I asked my doctor to write a new scrip using Brand Name Only....Synthroid, which he did and asked him Not to increase the prescription; but to see if using Synthroid instead of generic made a difference.

After three months, the doctor had me get more blood work. Using the Synthroid.....I Did Not Need to Increase my prescription. Since using Synthroid and not generic, I have been on the same prescription without an increase for the past couple of years.

Gerry

glenntaj · 01-21-2014, 07:22 AM

--doesn't have widespread control over metabolic rates and organ efficiency, but the pituitary is generally referred to as the master gland, in that it's hormonal signals control the thyroid and other glands.

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