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08-18-2015, 02:20 AM | #11 | |||
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Wisest Elder Ever
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greatest risk. Just visit any good Mad Cow site and see. The prions are concentrated in the central nervous system. Everything we consume as food and our water are contaminated Today. So it becomes a problem of doing the least dangerous. The cyanobacteria in our water is becoming concerning as well. Listeria in dairy and other processed food is becoming more common. All meats carry illness risks. Salmonella in peanuts and peanut butter and other veggies. Legionierres in the air we breathe. The list is really long and alarming. We are lucky indeed to dodge these "bullets" daily. So I think looking for more risk should be carefully evaluated And avoided if possible. Just my opinion.
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Last edited by mrsD; 08-18-2015 at 04:17 AM. |
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08-18-2015, 06:07 AM | #12 | |||
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Grand Magnate
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I strongly agree with what mrsD and DejaVu have said about Sphingolin - i would not touch it with the proverbial barge-pole.
Who knows what you are getting when you consume a product extracted from cattle brains? It could well include the misfolded form of prion protein - I doubt that the sellers of Sphingolin are capable of assessing this. Misfolded prion protein will kill you - it will (through well-understood biochemistry) convert your normal form of prion protein into its lethal form. The alleged benefit of Sphingolin is not worth the risk in my opinion.
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08-18-2015, 11:06 AM | #13 | ||
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Junior Member
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how about inosine?
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"Thanks for this!" says: | Patrick Winter (08-19-2015) |
08-19-2015, 04:05 PM | #14 | ||
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I have been wary of taking Inosine because of the fact that I heard it can cause gout and/or kidney stones.
"Although no side effects have been reported with the use of inosine, long-term use should be avoided. A very preliminary double-blind crossover study that enrolled 7 participants suggests that high doses of inosine (5,000 to 10,000 mg per day for 5 to 10 days) may increase the risk of uric acid–related problems, such as gout or kidney stones." So, would it be risky to take the 1000mg that is recommended for Neuropathy sufferers? Probably not. Tough call though. I am still considering it. I know there are some folks in this forum who take it and think they have seen its benefits. |
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08-19-2015, 04:20 PM | #15 | ||
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08-19-2015, 04:21 PM | #16 | ||
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08-19-2015, 04:25 PM | #17 | ||
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08-19-2015, 04:31 PM | #18 | ||
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I wonder though if the brain related damaged mylein is different than the small fiber related mylein. I don't see a them saying it applies to all mylein damage just the brain related. Maybe someone on here knows what's up with that. Of course its mice so, not exactly a confirmed cure. Would need clinical studies. but liek I say why is it reason to panic when mice get cancer from things like aspartame, but when we see something hopeful in mice we poo poo it and say, its just mice doesnt mean much. Judgoing by the comments section below it doesnt look very hopeful but those are MS patients, not SFN sufferers. |
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"Thanks for this!" says: | DejaVu (11-14-2015) |
08-19-2015, 04:46 PM | #19 | ||
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"Topiramate improves both symptoms and objective measurements of peripheral neuropathy while also lowering levels of total cholesterol, blood glucose, and blood pressure and promoting significant weight loss," Dr. Vinik said. Because previous trials had shown that high starting doses of topiramate can be toxic, the patients were administered 25 mg/day, titrated over 42 days to the maximum tolerated dose or 100 mg/day. The patients received the anticonvulsant for 84 more days. By the end of trial, dendrite length and peroneal nerve amplitude had increased, and total neuropathy scores had decreased from 14 to 11.8, Dr. Vinik reported. More important, "intra-epidermal nerve fibers actually grew back," he said. "That was the most dramatic observation." http://www.medscape.com/viewarticle/457287 |
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"Thanks for this!" says: | DejaVu (11-14-2015) |
08-19-2015, 04:49 PM | #20 | ||
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"Thanks for this!" says: | DejaVu (11-14-2015) |
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