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baba222 12-04-2015 08:50 PM

Article
 
http://www.upi.com/Health_News/2015/...9741449265570/

Hoping and praying is all I am saying!

Cliffman 12-05-2015 10:13 AM

Quote:

Originally Posted by baba222 (Post 1186893)
http://www.upi.com/Health_News/2015/...9741449265570/

Hoping and praying is all I am saying!

Good to know there's something being done for the future. :)

Thanks Baba for posting the article.

Cliffman :hug:

LouLou1978 12-05-2015 03:48 PM

hi there, I am currently being tested for this mutation, my bloodwork got lost last year so I have had to be re-tested for this. It has been found in 30% in people who have idiopathic small fibre neuropathy.

I believe there is a lot of work going into various Nav 1.7 blockers, one of which was convergence, I think they are now getting ready for stage 3 clinical trials:)

en bloc 12-05-2015 07:30 PM

I can only imagine the relief people might get with a breakthrough like this. But I do have one concern. People rely on pain to signal a problem and if you eliminate ALL pain, then how would one know if there is a medical problem? Someone might miss the early signs of cancer or other devistating conditions without feeling pain. What might they do about this? Does this only eliminate nerve pain?

baba222 12-06-2015 11:57 AM

Quote:

Originally Posted by LouLou1978 (Post 1186989)
hi there, I am currently being tested for this mutation, my bloodwork got lost last year so I have had to be re-tested for this. It has been found in 30% in people who have idiopathic small fibre neuropathy.

I believe there is a lot of work going into various Nav 1.7 blockers, one of which was convergence, I think they are now getting ready for stage 3 clinical trials:)

What is the exact test please?

baba222 12-06-2015 11:59 AM

Quote:

Originally Posted by en bloc (Post 1187004)
I can only imagine the relief people might get with a breakthrough like this. But I do have one concern. People rely on pain to signal a problem and if you eliminate ALL pain, then how would one know if there is a medical problem? Someone might miss the early signs of cancer or other devistating conditions without feeling pain. What might they do about this? Does this only eliminate nerve pain?

Yes. Not having pain might have some disadvantage.
I am not sure about just the nerve pain.

LouLou1978 12-06-2015 02:28 PM

Quote:

Originally Posted by baba222 (Post 1187061)
What is the exact test please?

Hi Baba 222, the genetic test is SCN9A - I'm in the UK , they do it is as part of the blood testing for SFN here.

:)

baba222 12-06-2015 05:41 PM

Quote:

Originally Posted by LouLou1978 (Post 1187081)
Hi Baba 222, the genetic test is SCN9A - I'm in the UK , they do it is as part of the blood testing for SFN here.

:)

Thank you so much.

Anyone did this here in USA? What is the procedure?

baba222 12-06-2015 05:57 PM

Quote:

Originally Posted by LouLou1978 (Post 1187081)
Hi Baba 222, the genetic test is SCN9A - I'm in the UK , they do it is as part of the blood testing for SFN here.

:)

I had 23 and me.
What is the particular SNP?
There are many SCN9A to my raw data.
TIA

kiwi33 12-06-2015 09:27 PM

Hi baba222

The information in this link lists many of the SNPs in SCN9A which have been associated with perception of pain; http://www.painresearchforum.org/res...rce/5937-scn9a .


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