Okay, I have Small Fiber Neuropathy (pain all over- numbness, burning, tingling) with some autonomic involvement--unable to discern temperature/vibration, leaking of urine).

The pain management is prescribing nucynta.

Anyone have experience with this one?

The side effect list has me really afraid.

I am in so much pain though...

Awaiting some good suggestions.

I was thinking of trying this too.


I tried tramadol and it doesnt do much. It makes me feel like I had coffee. Maybe it distracts me a little from the pain Ive only tried it 3 times. The dr says thats unusual. I am unusual
He said maybe nucynta would be better for me.
I am putting on my list for next time I see the dr.

Waiting to hear what others say...

It is a strong opiate, available in extended release or immediate release. If you're not on an ER med, that's probably the best option. Because it's a combo drug, it's actually effective in smaller dosages than other opiates.

I have tried many different opiate options and find both forms of Nucynta to be effective and have few side effects. You may experience drowsiness and constipation, and you will experience dependence after your body adjusts, of course. You should start at the lowest dosage available and be be very careful driving for a few weeks.

This is a schedule II narcotic, so you should understand the issues and inconveniences that go along with taking such drugs. (You need to realy trust your doctor and accept a certain amount of dependency on him or her, to go down this road.) If I was trying new meds, I would absolutely start with a trial of Low Dose Naltrexone before commiting to opiates. If that didn't work, Nucynta is a good place to start.

Don't expect you can take enough to be pain free. It'll allow you to have a lower baseline of pain through most of the day hopefully. Your doc can then decide if it would make sense to add in an IR opiate at some point as well.

Since I'm curious about this too, can I ask if you have tried tramadol and what your experience was?
Is the nucyinta more like oxycodone?

I'll send a pm.