Hello,
I did not realize I have not returned to post my result for the LDN. I tried it for a few months but eventually stopped because It did not seem to make any difference on my pain. However, I have found soaking/swimming in the ocean helping with my PN and RSD pains tremendously. It is too bad I can't access to a salt water pool or warm ocean. I accidentally discovered this while I was vacationing in Hawaii. Try it if you can access to a salt pool or warm ocean.
Good luck and take care,
Numb

Numb,
It's unfortunate that you had no success with LDN, but may I ask if you switched compounders before you threw in the towel? I ask, because it is well documented by Dr. Bihari that patients often get no potency, low potency or slow release LDN. This is why he advocated DIY LDN. You cannot fully trust the compounded medications, they are not FDA approved.

Recently one CRPSer wrote on the LDN FB page that she had instant relief.

Others write it took a year. I am now grateful that no doctor would prescribe it for me originally, which forced me into DIY. What if I had gotten no potency LDN I might never have recovered? I am more leery than average, due to a previous compounding failure that cost me half my hearing in one ear.

I also wonder if some think they will lose their business if LDN proves to be too successful, so they purposefully compound less than effective LDN.

I wish all the LDN products that do not work could be checked for potency.

Posting to add this info: LDN may not work if you have candida, yeast.

Biobased,
I diluted it with the distilled water. I did not have the pharm to compound it since my doctor had prescribed it at 50 mg which was the standard size.
I wonder was it the problem that might have reduced the effectiveness.
Thanks.
Numb

You may be in the twenty percent group who due to genetics will have no response or you may need to double dose. Some take it twice a day. Some take as little as 1mg with relief and some also need to take up to 12 mgs. I had no idea that there were so many variables, until I joined the endorphins FB group. Also, there are many stories of people stopping LDN because they believe it isn't working and afterward they realize there were subtle improvements.

I wish you had luck, because it is so distressing to read that you did not, considering my success.

I was able to dance twice at my daughter's wedding, but I did suffer the entire night and two days afterward with a flare. But these flares from "over doing it" while painful, cannot compare to what I suffered with before LDN. I believe if I had gotten LDN earlier I might have had a full remission.