Good morning ASB! Good point about maybe the dose is too high. I will mention it to her. After 4 years with no meds, lousy treatment from both her employer, doctors and insurance company and finally started to receive good treatment to control her pain after she was dumped from her company's payroll it was in these early days of treatment she tried methadone, percosets etc. slowly in order to find what worked better for her. After sometime it was vicodin (the strongest version) and 2 per-day 40mg ER oxycodin that she received the most relief. The other meds she takes are for muscle cramps, bone issues, lidocaine cream and inflamation meds. She refused to take any drug that will increase her weight. She has steadfast refused any evasive treatment at all cost, ever since her original injury, that caused her RSD including blocks, stimulators etc. Her fractured right wrist is still damaged from the reset the doctors performed (original injury) in which she still has torn cartilage and rubbing bone issues. To this day she wears a brace on her right arm and has been for 7 years. She has been warned by two doctors that physical therapy on her bad arm is a no no until she has surgery to correct this mess but are very afraid of her RSD spreading. There are no trapped nerves in her right hand and arm but sometimes I wonder about this, that there is a trapped nerve the EMGs missed causing her RSD symptoms. However she has had PT at GW hospital in Washington and several ketamine and lidocaine infusions. This Opana thread is very interesting because I can not recall reading anywhere a drug or procedure that has given those with RSD a high level of relief other than ketamine and or early detection followed by aggressive PT. I'll suggest to my wife the dosage issue and if she finally does receive Opana maybe the dose should start out lower around 10mg instead. I'm hoping she'll find more relief from her pain than she is now.

Jim,
We all wish Your Wife and you the best!
You should read the methadone thread as well.

Some doctors just write a prescription and slide it over to ya.
No explanation.
But, I think it's wise to start slow, and kind of "figure out" what this med does to/for you, one at a time!

Hope this helps, don't be afraid to PM me, if I can help.

Pete
Asb