AZ-Di - pardon my little side track.

MD- do you have any idea why they have not studied the effects of Ketamine for CRPS 2? I am assuming it doesn't work well with CRPS 2 due to the severity of the nerve injury that caused it to begin with? I was told in my case the nerve(s) that were damaged will not heal and that due to the location of damage that this will be continually irritated therefor it has been said that remission from the CRPS isn't likely. I am still optimistic but curious if you have any thoughts. Sorry the Ketamine caused such nasty effects and didn't work out for you.

Dear friends

With everything going on
THE MOST IMPORTANT THING YOU
CAN DO FOR YOURSELF IS LOG EVERYTHING
DOWN IT WILL BE YOUR SAVING OF ANY TURD
THAT MANY DO THROW BACK TO THE PATIENT
Log "ALL"

Someone who cares

I have full body, but it cannot be linked to my scs(plural) I have none in my neck, where the last one was planted, but my back is a train wreck. I have it in my eyes, and experienced no trauma there. I also was dxed this week with peripheral neuropathy and small nerve fiber neuropathy. Basically, my entire nervous system has gone insane I guess. Nerve diseases are a bucket of fun. I will say this. My scs's keep my leg and arm pain very minimal and I'm hoping with some tweaking this week we can cover the back spread. I have two. Surely the leads have contacts that will hit some of it. I had suspected back spread for awhile. After all this time, we finally have confirmation.

Praying you are......., well, doing well despite those things I just read....

Hey, can you see me waving??

I am, uh..... in the Dallas metroplex where I will be this coming week as I work through the bar exam...... again. Well, some people think I am doing a youthful person activity at my silver age.....

Anyway, figured I should give you a howdy do

Crps2 is very rare. Also, it is a more potent stimulus than crps 1. It's a genes environment interaction. One one end is spontaneous crps1 (probably largely genetic) and on the other end is major causalgia / crps 2 (largely environment)
Then there is everything in between from sprains to major crush multiple fractures. Major crush injuries probably nail numerous intermediate sized nerves. It's a spectrum.

Anecdotally, ketamine is not efficacious for crps2. There are just a couple positive case reports. Very weak evidence. I have seen some coma
Trials where they give huge doses and it
Works for a week and all comes back. They stopped doing it -
Bad for their numbers. For most crps patients, ketamine is
not great. For a lucky few it is great. It blocks the nmda and some opiod receptors. Very dirty drug. Crps has multiple mechanisms. One could make a cogent argument that it is the most complicated disease state. One thing is for sure- you only understand it if you have it!

I did 2 days a gram of ket each day and
Puked hallucinated and no pain relief. Never again.

Thanks MD for the added info on CRPS 1 & 2. My doctors all told me that "true causalgia or CRPS 2" is as you said very rare. They even went on to explain that the location where my iatrogenic nerve injuries occurred that caused the causalgia is even more rare - in fact my case is being written up for medical study in the journals of orthopedic surgery. I hope the article/study prevents this from happening to anyone else!!

Praying we all find ways to get maximum pain relief so we can enjoy every minute of this precious life,
Tessa