Thanks for the reply! I've been on Cymbalta now for a bit more than 5 weeks and my next appointment is the end of July. Since I've had this PN for 13 years, the relief I've got now from the pain is dramatic for me. Even "mildly discomfortable" is amazing.

I don't have the test results myself, but my neurologist specifically mentioned the B12 as being normal because 'd specifically mentioned this when I first spoke to her before the tests were done.

I have no real problems with the no-orgasm thing for another few weeks - it's not like my libido has evaporated -quite the contrary- and as long as my wife is ok with this, there are a lot worse things I've been through.

But I will discuss this Wellbutrin with my neurologist and see what the downside of that might be.

Get that B12 result! Doctors think 200pg/ml is "normal" and significant damage can result at this low level.

400pg/ml is the new "low" for normal but ranges don't reflect that.
In Japan it is even a higher!

If I have not given this new video to you yet, here it is:

http://www.youtube.com/watch?v=BvEiz...ature=youtu.be

This is my B12 informational thread which goes into detail about how to treat this orally, successfully, and explains testing.

Use the methyl version, as cyano is not active in the body and people can have genetic errors preventing activation of the synthetic cyano form.
http://neurotalk.psychcentral.com/thread85103.html

If I may suggest, do some research on it yourself beforehand, so you'll be able to discuss it from a more informed perspective. A couple of starting points might be cymbalta vs wellbutrin and cymbalta vs wellbutrin side effects.

Doc

On the RSD board I posted about my experience of the same issue. Noone warns you of how bad Cymbalta can be as it's the docs' new fad in pain relief. To me the lack of orgasm was a total dealbreaker as were the sleep problems. The other thing they don't tell you is how horrible it can be to come off Cymbalta. At your stage you have been on it only a little longer than I was and at half my dose so it may not be a problem. Be prepared though and google for more info. xx