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Anybody heard of PHENOCANE??

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Old 11-17-2008, 12:40 PM   #1
MelodyL
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Default Anybody heard of PHENOCANE??

Alan just got some literature from OxyLife. Alan is always going on the internet and researching alernative pain management stuff, and I guess he found this one.

They included a free sample of PHENOCANE.

Here's a link to their website.
I am reading the brochure and it mentions that this is not FDA approved. but all the literature is about pain management and anti-inflammation.

http://www.seacoastvitamins.com/prod...oducts_id=1808

I gather this is not applicable for neuropathy, but might be for some sort of arthritic pain???

Comments??

Melody
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Old 11-17-2008, 02:30 PM   #2
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Lightbulb curcumin

yes, you can try that. It might even help your diabetes.
http://www.nutraingredients-usa.com/...benefits-study



That product? Nope.

It has a glaring error in explaining what phenylalanine does in the body:

Phenocal site:
Quote:
dl phenylalanine: Otherwise called DLPA. DLPA is a beneficial amino acid that is noted for helping the body maintain higher levels of serotonin. Serotonin is a hormone produced in the brain that promotes good feelings and has been proven to elevate mood, which then helps reduce feelings of pain.


reality:
Quote:
Other biological roles

L-phenylalanine can also be converted into L-tyrosine, another one of the DNA-encoded amino acids. L-tyrosine in turn is converted into L-DOPA, which is further converted into dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline). The latter three are known as the catecholamines.

Phenylalanine uses the same active transport channel as tryptophan to cross the blood-brain barrier, and, in large quantities, interferes with the production of serotonin.
from http://en.wikipedia.org/wiki/Phenylalanine
Anyone with high blood pressure should not take this supplement. Also, phenylalanine is 1/2 of the ingredients in aspartame (Nutrasweet).

Nattokinase thins the blood and may interfere with blood thinners. It is normally fairly expensive.

This mixture of supplements is pretty inexpensive so I suspect the actual amount of ingredients is low/capsule. Fitting therapeutic amounts of all of those in one item, is a trick..typically only a small amount of each is in each capsule. (a common supplement scam)

So get some curcumin...that's what I'd suggest.
Puritan's has some good extracts..I use their ginger all the time.

Curcumin is getting alot of attention now as an anti-inflammatory. You'd need at least 2 caps of the extract a day, maybe 3.
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Last edited by mrsD; 11-17-2008 at 10:15 PM.
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Old 11-17-2008, 03:27 PM   #3
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This is what I found on it when looking on the web.

A combination of natural ingredients acts as an anti-inflammatory and inhibits the Cox-2 enzyme without the side effects caused by prescription drugs.

This extremely effective supplement stops pain and stiffness in as little as 24 hrs and, with continued use, will keep inflammation under control, giving you greater mobility and movement.
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Old 11-17-2008, 03:47 PM   #4
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Now you all know why I love Mrs. D!!!!

I won't be taking this thing any time soon.

Glad I put it up on the boards.

Melody
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Old 11-23-2008, 09:20 AM   #5
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mel, do try the curcumin,,,neat stuff.....check out pubmed....many,many articles
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Old 11-23-2008, 10:34 AM   #6
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Quote:
Originally Posted by pabb View Post
mel, do try the curcumin,,,neat stuff.....check out pubmed....many,many articles
Just went to pubmed. Read some of the articles. Very interesting. I had heard about turmeric. Can't find it in my local stores. but I do have CUMIN in my home and I put it on my fish. Is this almost as good as Curcumin, (or does it have absolutely nothing to do with Curcumin?).

Thanks in case you know.

Melody
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Old 11-23-2008, 11:09 AM   #7
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Lightbulb no, cumin is different.

Curcumin is in curry spice. So is cumin. But they come from different plants, and
are different chemically.

I use a Pondecherry curry in our soups, stews and even
chili. I make chili out of chicken and pork, more than I do with
beef.

I don't use as much as you'd do for curry, but used lightly to
moderately..taste it to your liking..I find it gives a nice body to
soups/stews and makes the house smell really nice. Hubby always comments on the aroma!

Curcumin needs oil to be absorbed so it is thought to work better from foods. But I just found a LEF article on adding piperine (Bioperine) to it to make it more absorbable.

This is the newest thread from PD on it. Those forum members use and post about it alot. So do a search there too.
http://neurotalk.psychcentral.com/sh...142#post413142
read this thread-- there is discussion on smaller doses vs. larger ones.
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Last edited by mrsD; 11-23-2008 at 11:25 AM.
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Old 11-23-2008, 11:41 AM   #8
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"Curcumin is a natural phenolic component of yellow curry spice, which is used in some cultures for the treatment of diseases associated with oxidative stress and
inflammation. Curcumin has been reported to be capable of preventing the death of neurons in animal models of neurodegenerative disorders, but its possible effects
on developmental and adult neuroplasticity are unknown. In the present study, we investigated the effects of curcumin on mouse multi-potent neural progenitor cells (NPC) and adult hippocampal neurogenesis. Curcumin exerted biphasic effects
on cultured NPC; low concentrations stimulated cell proliferation, whereas high concentrations were cytotoxic. Curcumin activated extracellular signal-regulated
kinases (ERKs) and p38 kinases, cellular signal transduction pathways known to be involved in the regulation of neuronal plasticity and stress responses. Inhibitors of ERKs and p38 kinases effectively blocked the mitogenic effect of
curcumin in NPC. Administration of curcumin to adult mice resulted in a significant increase in the number of newly generated cells in the dentate gyrus of hippocampus, indicating that curcumin enhances adult hippocampal neurogenesis. Our findings suggest that curcumin can stimulate developmental and adult hippocampal neurogenesis, and a biological activity that may enhance neural plasticity and repair."
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Mrs. D. The only part of the above paragraph that I understood was where it mentioned hippocampal. (This refers to short term memory right??) Or am I dead wrong here?

If this curcumin helps THAT, I'll go out and buy some tomorrow.

But do me a favor. Talk to me like I'm brain dead and translate the rest.

For example.

What this means is that if you use curcumin in your diet, you'll have a better memory, live longer, etc.

Because I couldn't understand ANY of it. I feel like a dodo bird among swans.

But hey, I'M LEARNING ALL ABOUT SPROUTS!!!

lol
Melody
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Old 11-27-2008, 05:05 PM   #9
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Quote:
Originally Posted by MelodyL View Post
"Curcumin is a natural phenolic component of yellow curry spice, which is used in some cultures for the treatment of diseases associated with oxidative stress and
inflammation. Curcumin has been reported to be capable of preventing the death of neurons in animal models of neurodegenerative disorders, but its possible effects
on developmental and adult neuroplasticity are unknown. In the present study, we investigated the effects of curcumin on mouse multi-potent neural progenitor cells (NPC) and adult hippocampal neurogenesis. Curcumin exerted biphasic effects
on cultured NPC; low concentrations stimulated cell proliferation, whereas high concentrations were cytotoxic. Curcumin activated extracellular signal-regulated
kinases (ERKs) and p38 kinases, cellular signal transduction pathways known to be involved in the regulation of neuronal plasticity and stress responses. Inhibitors of ERKs and p38 kinases effectively blocked the mitogenic effect of
curcumin in NPC. Administration of curcumin to adult mice resulted in a significant increase in the number of newly generated cells in the dentate gyrus of hippocampus, indicating that curcumin enhances adult hippocampal neurogenesis. Our findings suggest that curcumin can stimulate developmental and adult hippocampal neurogenesis, and a biological activity that may enhance neural plasticity and repair."
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Mrs. D. The only part of the above paragraph that I understood was where it mentioned hippocampal. (This refers to short term memory right??) Or am I dead wrong here?

If this curcumin helps THAT, I'll go out and buy some tomorrow.

But do me a favor. Talk to me like I'm brain dead and translate the rest.

For example.

What this means is that if you use curcumin in your diet, you'll have a better memory, live longer, etc.

Because I couldn't understand ANY of it. I feel like a dodo bird among swans.

But hey, I'M LEARNING ALL ABOUT SPROUTS!!!

lol
Melody
well, melllllll, i think you found THE most compex listing on pumed.....i think what it is saying is it helps with repair..and increases plasticity which is ..hmm the ability of the cells/brain to adapt....it does cross the blood brain barrier... many things dont, it seems to help with insulin resistance and helps with mood,via two pathways apparently....the MAO and possibly reducing intracranial inflammation.....i am not sure of how it helps with the insulin resistance....and, no not cumin.....turmeric is the spice.....mccormack does put it out.....i would be surprised if the market doesnt carry it....ask for the person who does the ordering for that dept......good luck
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Old 11-28-2008, 07:04 AM   #10
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Thanks very much.

I shall endeavor to go and find Turmeric.

I want to have happy brain cells.

lol

Melody
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