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Old 12-28-2008, 08:56 AM #1
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Default Magnesium and B6
Med Clin (Barc). 2008 Nov 22;131(18):689-92.
An open study evaluating the efficacy and security of magnesium and vitamin B(6) as a treatment of Tourette syndrome in children.
[Article in Spanish]
PubMed Article
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Old 01-12-2009, 08:05 AM #2
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Default 'The Diagnosis of Tourette's Syndrome: Communication and Impact.'
PubMed

Clin Child Psychol Psychiatry. 2009 Jan;14(1):13-23.

The Diagnosis of Tourette's Syndrome: Communication and Impact.
Rivera-Navarro J, Cubo E, Almazán J.

Salamanca University, Spain.

<snipped abstract>

Quote:
The most important conclusion was that the current method for communicating the diagnosis of TS to patients and relatives should be improved to facilitate better understanding and interpretation.
Last edited by Lara; 01-12-2009 at 08:39 AM.
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Old 01-12-2009, 08:10 AM #3
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Default Charcot's contribution to the study of Tourette's syndrome
PubMed
Charcot's contribution to the study of Tourette's syndrome

We review the history of Tourette syndrome, emphasizing the contribution of Jean-Martin Charcot.

Teive HA, Chien HF, Munhoz RP, Barbosa ER.
Movement Disorders Unit, Hospital de Clínicas, Hospital de Clínicas, Federal University of Paraná, Curitiba PR, Brazil.

__________

Full text...

Associação Arquivos de Neuro-Psiquiatria

Arquivos de Neuro-Psiquiatria
Print ISSN 0004-282X
Arq. Neuro-Psiquiatr. vol.66 no.4 São Paulo Dec. 2008
Charcot's contribution to the study of Tourette's syndrome

Hélio A.G. Teive; Hsin Fen Chien; Renato Puppi Munhoz; Egberto Reis Barbosa

Movement Disorders Unit, Neurology Service, Hospital de Clínicas, Federal University of Paraná, Curitiba PR, Brazil
Movement Disorders Clinic, Department of Neurology, Hospital das Clínicas, University of São Paulo, São Paulo SP, Brazil
Last edited by Lara; 01-12-2009 at 08:39 AM.
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Old 01-12-2009, 08:26 AM #4
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Exclamation Neuropsychiatric Disorders Associated With Streptococcal Infection
J Am Acad Child Adolesc Psychiatry. 2008 Aug 21.

Neuropsychiatric Disorders Associated With Streptococcal Infection: A Case-Control Study Among Privately Insured Children.

Leslie DL, Kozma L, Martin A, Landeros A, Katsovich L, King RA, Leckman JF.

Dr. Leslie is with the Department of Health Administration and Policy, Medical University of South Carolina; Ms. Kozma is with the Department of Chemistry, Yale University; and Drs. Martin, Landeros, King, and Leckman and Ms. Katsovich are with the Child Study Center, Yale University School of Medicine.

Quote:
OBJECTIVE:: To assess whether antecedent streptococcal infection(s) increase the risk of subsequent diagnosis of obsessive-compulsive disorder (OCD), Tourette syndrome (TS), other tic disorders, attention-deficit/hyperactivity disorder (ADHD), or major depressive disorder (MDD) in a national sample of privately insured children.
PubMed Abstract

Quote:
CONCLUSIONS:: These findings provide epidemiologic evidence that some pediatric-onset neuropsychiatric disorders, including OCD, tic disorders, ADHD, and MDD, may be temporally related to prior streptococcal infections. Whether this is the result of a nonspecific stress response or secondary to an activation of the immune system remains to be determined.

Journal of the American Academy of Child & Adolescent Psychiatry:
October 2008 - Volume 47 - Issue 10 - pp 1166-1172
doi: 10.1097/CHI.0b013e3181825a3d
New Research
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Old 01-12-2009, 08:38 AM #5
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Default Tic disorders and ADHD - from Tourette Syndrome International Database Consortium ...
PubMed

Eur Child Adolesc Psychiatry. 2007 Jun;16 Suppl 1:15-23.
  • Erratum in:
  • Eur Child Adolesc Psychiatry. 2007 Dec;16(8):536.

Tic disorders and ADHD: answers from a world-wide clinical dataset on Tourette syndrome.

Freeman RD; Tourette Syndrome International Database Consortium.

Quote:
CONCLUSION: Subjects with TS have high rates of ADHD and complex associations with other disorders. Clinically the findings confirm other research indicating the importance of ADHD in understanding the behavioural problems often associated with the diagnosis of TS. Additional ADHD comorbidity should be taken into account in diagnosis, management, and training.
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Old 01-12-2009, 08:47 AM #6
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Default Streptococcal infection and exacerbations of childhood tics and OC symptoms
PubMed Abstract

Pediatrics. 2008 Jun;121(6):1188-97.
  • Comment in:
  • Pediatrics. 2008 Nov;122(5):1157; author reply 1157-8.

Streptococcal infection and exacerbations of childhood tics and obsessive-compulsive symptoms: a prospective blinded cohort study.

Kurlan R, Johnson D, Kaplan EL; and the Tourette Syndrome Study Group.
University of Rochester School of Medicine,
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Old 01-12-2009, 08:50 AM #7
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Default Air swallowing as a tic
PubMed

J Psychosom Res. 2008 Nov;65(5):497-500. Epub 2008 Oct 1.
Air swallowing as a tic.
Weil RS, Cavanna AE, Willoughby JM, Robertson MM.

Institute of Neurology, Queen Square, London, UK.

Quote:
The authors present a patient with Gilles de la Tourette syndrome who developed abdominal distension and bloating due to air swallowing. We suggest that this air swallowing may have been due to a tic.
Last edited by Lara; 01-12-2009 at 09:14 AM.
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"Thanks for this!" says:
Chemar (01-12-2009)
Old 05-22-2009, 03:21 PM #8
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Default Immunopathogenic mechanisms in tourette syndrome
http://neurotalk.psychcentral.com/post499139-46.html
I already posted this one but I'll leave it here and quote the material regarding T cells.

PubMed
Mov Disord. 2009 Apr 7.
Immunopathogenic mechanisms in tourette syndrome: A critical review.
Martino D, Dale RC, Gilbert DL, Giovannoni G, Leckman JF.

Department of Neurological and Psychiatric Sciences, University of Bari, Bari, Italy.

<snipped abstract>
Quote:
Finally, a general predisposition to autoimmune responses in TS patients is indicated by the reduced frequency of regulatory T cells, which induce tolerance towards self-antigens. Although the pathogenic role of immune activation in TS has not been definitively proven, a pathophysiological model is proposed to explain the possible effect of immunity upon dopamine transmission regulation and the generation of tics.
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