My pulse is generally a lot higher than it should be.

When I wake up after a good night it is around 60. It goes up to 95 when I have a stressless day inside the house. While sitting it remains around 95. Light Excercise will bring it up to 120 or more.

When I am outside the house it stays at 120 and more even when sitting. I have no chance to bring it down than. So stress has to play an important role. I will try the beta blocker as long as I take amitryptiline.

Have you been to a cardiologist? THis sounds like something that should be looked at. You may want to ask about having your heart listened to, and an EKG and/or echocardiogram, and a tilt table test.

Could a persistent pulse rate of 95/120 have a negative effect on the healing? What does the research say?

I doubt that pulse rate effect healing. I have never read anything that suggests a problem.

What do you use to check your pulse ? Does it check your blood pressure, too?

My bp measuring device also shows the pulse rate. It is just like you exercise the whole day when the rate stays that high. I dont think that this can be good.

Today I even had 130-150 for a short time, only because of light activities at home.

And I also noticed that a bad sleep and too much cognitive activities(thinking is enough) are a trigger.

Speaking from a medical background, your resting heart rate (based on so many things) should be under 100. I don't get too nervous as a health care worker unless resting its over 120. But, I think that people who have increased stress and anxiety have higher heart rates. EKG showing Tachycardia doesn't show anything really. Have a stress test? That may help show some stuff. I have had one. It's not bad.

Reasons other than stress your heart rate could be elevated while resting: PSVT(Paroxysmal Supraventricular Tachycardia) Fancy big word that says your top chambers of your heart beat way faster and do not effectively pump any blood.
Infection. You may have a small infection that you don't notice. Check your temp, monitor yourself for that.
Headaches. They can raise your pulse
Caffeine. Definitely can raise your pulse
Dehydration. Try drinking some gatorade/powerade to get your fluids up. Drink lots of water also.
Blood sugar issues. Check your sugar if you have a glucometer at home. If not, just watch what you eat. Notice any changes.

Let me know how you are. Take care.

Thanks for your post medic. I will check each point you mentioned.

My pulse rate was absolutely crazy today. I was at home all day Sometimes down at 60 while sitting, sometimes reaching 140 or more while standing and slow walking. Now I have constant 95 while resting in bed. Really strange. No chance to bring it down.

I reduced amitryptiline to 10 mg. I doubt it comes from that.