Any thoughts
could this be effecting recovery I came across this when doing research as to my CSF leak




Atenolol and all beta blockers undoubtedly save life's and no one should just stop taking them , I will be consulting my doctors to see if there is an alternative medication, I can take for my high blood pressure that dose not affect the choroid plexus and CSF production, as most of us on this board( CSF leak forum ) know CSF high ,low volume /pressure all have painful and devastating affects on our lives , also our cognitive ability s, as we know our CSF supports, nourishes, cleanses by removing spent neurons and toxins from our brain and spinal cord in a cyclical motion . So from this article
ARTICLES
The nocturnal increase in human cerebrospinal fluid production is inhibited by a beta 1-receptor antagonist

C. Nilsson, F. Stahlberg, P. Gideon, C. Thomsen and O. Henriksen
Department of Medical Cell Research, University of Lund, Sweden.

A circadian variation in human cerebrospinal fluid (CSF) production has recently been demonstrated using magnetic resonance phase imaging. A nightly peak in CSF production was found at approximately 0200, when production is approximately twice the daytime values. In the present study, we have investigated the effect of a beta 1-receptor antagonist, atenolol, on the production of CSF, specifically the nocturnal production peak. CSF production was measured in fourteen healthy volunteers of both sexes in the time interval 1500-1800, with or without drug administration (100 mg orally) at 1800, and a second measurement was made in the time interval 2300-0200. In the absence of drug administration, all nine volunteers showed a significant increase in CSF production at night, from 0.34 +/- 0.06 ml/min in the time interval 1500-1800 to 0.61 +/- 0.05 (SE) ml/min (P < 0.005), confirming the presence of a circadian variation in these individuals. One week later, the experiment was repeated in five of these volunteers, plus an additional five volunteers, but with the administration of 100 mg atenolol orally immediately after the first measurement (at 1800). In five of the volunteers a decrease in CSF production was seen at midnight compared with daytime production values; in two volunteers CSF production remained unchanged, while three volunteers showed increased production. The average CSF production was 32% lower at night (0.27 +/- 0.10 ml/min) compared with the afternoon (0.40 +/- 0.07 ml/min), after administration of atenolol (P = 0.37).(ABSTRACT TRUNCATED AT 250 WORDS)


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the research suggests that atenolol lowers CSF production by 32% at night now my partner has told me I have fits in my sleep ( interesting ) for those who don,t know me . I suffered head trauma had a nasal CSF leak from skull fractures I think I am still leaking and starting tests soon , so for any one with with CSF leaks or in fact any one with a neurological condition ,are these type of drugs in conflict with our health ? undoubtedly beneficial to our cardiovascular system, but compromising our CSF production / balance of this delicate system? ( a true dichotomy ) I have been on atenolol 100mg for two years many of my problems maybe due to the TBI and the leak but anything that is effecting that system cant be helping us to heal

link to help you understand issue,s

http://www.cerebrospinalfluidresearc...content/5/1/10

vini,

I have seizure like body jerks at night too. I take Neurontin to help settle them down. Is there any research that suggests fits from low CSF pressure? I did a google and cannot find anything.

Is there a chance they will try to plug your leak? The situations where I heard of using the patients blood to plug the leak concerned a lumbar puncture and a leak in the back of the sinus.

I hope they find an accessible leak location that they can treat.

I have atenolol and propanolol on the shelf for the occasional BP spike. My adrenal system sometimes acts up from sensory over-stimulation and my BP can get so high it is life threatening. When it hits 195/150, I feel like I am going to explode. Usually, it is 115-125 / 65-80.
I have also had extremely low BP, 85-90/40-45. Then I feel like I am made of lead.

Brain injuries sure can through a mess of chaos at us.