HLA Testing

11-07-2006, 09:04 PM

I found some information:

http://www.questdiagnostics.com/bran...u_gen/faq.html

http://www.cdc.gov/ncidod/eid/vol3no1/singh.htm

http://www.thyroidmanager.org/Chapter7/7-text.htm
refer to part 3. Antigen Presentation On MHC Molecules, complex but does have good info

http://www.jci.org/cgi/content/full/116/8/2226
specific to Celiac

http://www.uchsc.edu/misc/diabetes/oxch8.html
I found this interesting because I can now go to my mother w/proof that her addison's disease is linked to my Celiac by the HLA DQ 2

http://www.endotext.org/diabetes/dia.../diabetes5.htm
Interesting notation in the link:

Quote:

When an individual presents with type 1A diabetes it indicates that they and their relatives have an increased risk of having or developing a series of autoimmune disorders(11). Celiac disease, hypothyroidism, hyperthyroidism, Addison’s disease and pernicious anemia are some of the most prominent associated diseases. For example approximately 1/20 patients with type 1 diabetes have celiac disease(13;14). Most of these patients are asymptomatic and the disorder is only discovered if anti-transglutaminase autoantibodies are measured and individuals with positive antibodies biopsied. In that the therapy for celiac disease, namely gluten avoidance, is highly effective, at the Barbara Davis Center we routinely screen all type 1 diabetic patients. We also screen for thyroid disease and for Addison’s disease (21-hydroxylase autoantibodies)(15).

http://www.annals.org/cgi/reprint/142/4/289.pdf
specific to celiac - very good

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