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Old 03-17-2010, 07:17 PM #1
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Default Tysabri + Chemo

If its posted elsewhere steer me in the direction. If not, what have if any of you's combined with Ty? My doc discussed one quickly with me explained the risks mostly. My MRI from today shows a huge lesion that wasnt there 1 yr ago. Numbness to prove it. Chemo drugs + Ty anyone?
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Old 03-17-2010, 09:32 PM #2
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I don't know anyone who has combined chemo with Ty, but I would be terrified at what the possible side effects could do to my body.

If Tysabri is not doing the job for you, then why don't you switch rather than add on?

Good wishes.
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Old 03-17-2010, 10:30 PM #3
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Are you saying that your doctor suggested ADDING chemo to the ty?? Ummm....NOT SO MUCH!! Chemo is an immunosupressant....cannot be given while on Ty...it is contraindicated. I had to wait at least 30 days AFTER having Ty before having chemo! And some doctors even suggested waiting longer than 30 (which I did). In fact, I don't think any Touch center would allow you to have ty if you told them you had chemo. I'd double check this...but I know there's NO way I'd mix chemo with ty.

Please double check this!!

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Old 03-18-2010, 07:34 AM #4
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AGreed! that would be a HUGE risk to take! Please, make your DR explain himself, and why he would be willing to take such a large risk or PML for you?

This doesnt sound safe, nor approved by any guidelines I have ever seen.

I hope you can get some answers.
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Old 03-18-2010, 04:52 PM #5
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Nope to the chemo and Tysabri. Tysabri is a monotherapy. No immunosuppressants allowed. Limited use of steroids to treat relapse if they are SURE it's a relapse. No certified infusion center will infuse Tysabri along with chemo. Any doctor prescribing Tysabri knows that or they shouldn't be prescribing Tysabri.

I'd be asking a lot more questions.
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Old 03-18-2010, 06:52 PM #6
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Problem is im a paraplegic for 20yrs losing my hands to MS. I was diagnosed late cause I couldnt walk to begin with and didnt show symptoms till my face was numb one morning almost 4 yrs ago. Doc and I already discussed the possible outcome of Ty and Chemo. Told him id sign a release.

Honestly I wanted to try adding Estriol to Copaxone last yr but neuro wanted nothing to do with Estriol. Its just a estrogen. Sheesh look at the possible outcomes of Ty and thats what hes was comfy with. I need something fast cause im losing feeling on a weekly basis.

This is what ended easy access to estriol
http://www.fda.gov/NewsEvents/Newsro.../ucm116832.htm

Im getting off track. So what can be combined with Ty then?
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