I came across an abstract from the annual meeting of the American Academy of Neurology (AAN) about a study done on patients who switched to getting Tysabri every other month.

It's quite interesting! 42 stable patients who had been on Tysabri for 2+ years or more switched to every 8 weeks. Over the next 2 years they stayed on the 8 week plan getting an MRI every 6 months to chart their disease.

3 of the patients couldn't tolerate the change because of MS fatigue. The other 39 stayed on the 8 week plan and had no relapses or changes on the MRI over the next 2 years. That is 92% of the participants stayed the same!!! This is remarkable for several reasons.

It looks like every other month is really just as good as every month!! This could save people money. I wonder if it reduces PML risk? It definitely lessens your chance for infections which is why I did it. I stopped getting UTIs when I switched to every 8 weeks. I've been on the 8 week plan for 2 1/2 years now. No relapses and no MRI changes. . Again, 92% STAYED THE SAME.

Of course Biogen wouldn't necessarily be happy for people to switch because they would lose BIG dollars.

http://www.neurology.org/cgi/content...4-939fc00108ad