mrsD maybe it was guaifenesin I saw not the other. Honestly, I copy paste both g words because they're not in my brains dictionary My bad.
I used a 3mL syringe to squirt exactly 2.5mL/7.5mg before sleep last night. Cured? hah no but it tasted good. I'll try it for a week.

Don't expect to see any significant change after only a week or two of use.
I do not expect, nor have I experienced a cure of my PD from dextromethorphan. I do know that, having taken it faithfully for the past 6-7 years, I am not aware of anyone else who has been diagnosed with PD for 11+ years who has progressed as slowly as I have. Therefore, I'm convinced that the low-dose approach with the drug is providing me some neuroprotection.

Hi there. I've been reading all these older post for some time now. Finally joined today. My story isn't MS, PD, Alzheimer's or any of the typical PBA nuedexta treatments, but is brain injury none the less. My son has it and this DM stuff is fasinating to say the least. Started with a post on another site about PBA and when I read it was helping with swallowing and talking in ALS patients I was on the hunt for info. Well we finally tried DM OTC for 6 days. Just a childs dose once a day(he`s 31 years old). Then he looked peaked like any new drug does so I stopped. Nice thing is I`ve seen some weird recovery happening that after 6 years is just awesome and seen it from day 1. Haveing a hard time finding info on brain injury let alone anoxic brain injury so I`ve put out a request on several sites for helpful info. 2 brain injury sites and an alzheimers site so far. One other caregiver is trying it right now that I chat with everyday with some good reports so far. We happened to go to his physiatrist a couple weeks after stopping it and I was telling her what I was seeing and I think she new I was. My thought was that new drugs happen to lower his BP so she did write a script for a med to help him ease into taking it again. I told her I was not going to just yet. I`m still in awe at what he has gained. Just still looking for more info I guess before we get started again now as its been over a month and still he is better. But how much better could he get? Hard to get hopes up you know. Thanks for all the good reads so far and I`m gonna check out this site further. Have a great day everyone and I`ll be hanging around searching for more info. Ruth

Welcome Mom..

Welcome Ruth!

Did you start your son back on the dextromethorphan? I think it's interesting that he started improving after taking it and only took it for 6 days. Keep us posted on how he is doing.

Thanks, Not yet but so tempted. Its been a full month now since he had a dose, wow where does the time go. Hes still doing good things but it seems he might be starting to slow down a bit again with not as much energy I guess you`d say. Hard to tell as he`s pretty non verbal. Talks real good in his sleep though. LOL I`ll let you know when I start and what dose I decide on. I`m thinking about even a lower dose or even a once a week dose to see how much he really needs to see improvement and maybe sidestep the low BP problem so I don`t have to add that other pill. I`m still just in awe at times with some of the things he can do that he had such a hard time with or couldn`t do pre-cough syrup. Who would`a guested? We did however use the one that is extended release and his doc said that was fine when I asked her. Still seems to have done something in the great dept.

I know that guaifenesin is used for fibro with some good results although some doctors refute this. Well some doctors refute fibro. I don't know what it does to the fibro whether it is the pain or something else

Learn something new everyday, thanks, I`ll keep that in mind. Ruth

Well I just read this and it plays into the why hes still doing well weeks after using DM. This is for treatment resistant depression and is using ketamine but from what I understand they work alike. I have no idea if the lad is depressed or not but I do know that I`ve seen some major motor movement improvements and I like it. Just thought I`d share as the time line of effectiveness is interesting. More towards my once a week a doseing I was concidering trying. Might need a few days of childs dose first to get back to that saturation point. I`m gonna keep reading and pondering. Ruth

Evidence for Safety in Antidepressant Use:


RESULTS: Ketamine elicited minimal positive psychotic symptoms. Three patients experienced significant but transient dissociative symptoms. Side effects during and after each ketamine infusion were generally mild. The response criterion was met by nine patients after the first infusion as well as after the sixth infusion. The mean (SD) reduction in MADRS scores after the sixth infusion was 85% (12%). Postketamine, eight of nine patients relapsed, on average, 19 days after the sixth infusion (range 6 days-45 days). One patient remained antidepressant-free with minimal depressive symptoms for >3 months.

CONCLUSIONS: These pilot findings suggest feasibility of repeated-dose IV ketamine for the acute treatment of TRD.

Ruth I don't know if you have fibro or not but when my sister first got it I did a lot of reading about the treatment. I believe there is a fibro forum here on Neurotalk and that's where I learned about it.