[Natalie8]

This article is fascinating and only confirms my long held suspicion that weight often matters when it comes to drug dosing. Smaller, thinner folk just build up a higher saturation of Tysabri and then are likely more immunosuppressed.

http://www.clinicalneurologynews.com...duced-pml.html

What they are suggesting is that people who are JCV + who are 70 kg. or less move to 5-6 week dosing schedules to lower PML risk instead of every 4 weeks.