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Vitamin D and MS ?

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Old 06-20-2008, 06:43 PM #1
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Default Risk assessment for vitamin D
I think it is very unwise for amost anyone to exceed 10,000 IU of Vitamin d3.

I take a total of 4,200 IUs of Vit D3 in supplement form daily.

jackD

p.s UL = Upper Level intake safe amount


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1: Am J Clin Nutr. 2007 Jan;85(1):6-18.

Risk assessment for vitamin D.

Hathcock JN, Shao A, Vieth R, Heaney R.

Council for Responsible Nutrition, Washington, DC 20036-5114, USA.

The objective of this review was to apply the risk assessment methodology used by the Food and Nutrition Board (FNB) to derive a revised safe Tolerable Upper Intake Level (UL) for vitamin D. New data continue to emerge regarding the health benefits of vitamin D beyond its role in bone.

The intakes associated with those benefits suggest a need for levels of supplementation, food fortification, or both that are higher than current levels. A prevailing concern exists, however, regarding the potential for toxicity related to excessive vitamin D intakes.

The UL established by the FNB for vitamin D (50 microg, or 2000 IU) is not based on current evidence and is viewed by many as being too restrictive, thus curtailing research, commercial development, and optimization of nutritional policy.

Human clinical trial data published subsequent to the establishment of the FNB vitamin D UL published in 1997 support a significantly higher UL.

We present a risk assessment based on relevant, well-designed human clinical trials of vitamin D.

Collectively, the absence of toxicity in trials conducted in healthy adults that used vitamin D dose > or = 250 microg/d (10,000 IU vitamin D3) supports the confident selection of this value as the UL.

PMID: 17209171 [PubMed - indexed for MEDLINE]
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Old 06-20-2008, 07:00 PM #2
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Quote:
Originally Posted by jackD View Post
I think it is very unwise for amost anyone to exceed 10,000 IU of Vitamin d3.

I take a total of 4,200 IUs of Vit D3 in supplement form daily.

jackD

p.s UL = Upper Level intake safe amount
Too much of a "good" thing can actually be really bad if not toxic. I have seen it over and over. Very sad.
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Old 06-20-2008, 07:18 PM #3
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Yeah not sure I would exceed 1000 iu a day. Slow and steady is the way I am building mine back up.
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Old 06-20-2008, 09:05 PM #4
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This is the most comprehensive information about Vitamin D I have yet to find. As you get towards the bottom ( long) it explains why doses are being given above 2000 IU a day.

It is very interesting because it cites how steroids affect calcium and Vitamin D, and how other medications alter absorption.

http://ods.od.nih.gov/factsheets/vitamind.asp

For more info google: vitamin + D + absorption

Thanks for the article from the Journal of Clinical Nutrition!
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Old 06-21-2008, 07:22 AM #5
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I cant keep my Vit D level up. I have taken lots of different over the counter stuff too. I was recently placed on Rx stuff. I hope that helps. I already feel better after just a couple of weeks on it.
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