I noticed a BIG difference in my spasticity pain almost immediately (within a few days), but I was on 3.0 mg from the beginning too. I had suffered with that pain, to the point that I had to wear braces on my limbs every night and many days, for almost 2 yrs. I have only had to use one brace, once, since I started on LDN.

It could be either thing that's helping you, Frank; going off other meds OR going on LDN. I waited several months to try weaning off Celexa because I wanted to know which drug was helping/hurting. Ultimately, I knew it was LDN that helped with certain things, and Celexa that caused me other side-effects.

After you've stabilized at 3.0mg or 4.5mg, you can try stopping it for a few days to see.

Cherie