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Old 11-07-2008, 02:10 AM #11
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lady_express_44 lady_express_44 is offline
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lady_express_44 lady_express_44 is offline
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Quote:
Originally Posted by mom2five View Post
My neurologist said no to the LDN Rx. She told me that she wants to see what happens with the clinical trials in San Francisco first, but that could be years.

I will try my primary care physician next. I would love any tips on how to get the Rx for LDN. I'm frustrated...really don't want to do my Avonex shot this Sunday.
The clinical trial in San Fran has finished, and at least some results have been published:

"Dr. Bruce Cree from the University of California, San Francisco, presented the results of his 8-week clinical trial of LDN in multiple sclerosis. The trial was a single center, randomized, double masked, placebo controlled, double-cross over study of naltrexone using 4.5 mg daily to evaluate Quality of life. The multiple sclerosis quality of life inventory (MSQLI) was used for the evaluation. The study involved 80 subjects and 70 patients completed the trial.

Results
Compared to the placebo, LDN significantly improved the mental health component summary score. Quality of life was improved on all parameters. Pain was also reduced by LDN. The study showed that short-term use of low dose naltrexone was well tolerated and appears to benefit mental components of MS. Physical improvements were not noted in this study, which could be related to its short duration."

http://autoimmunedisease.suite101.co...iple_sclerosis

I'm not sure why she would have been waiting for those results though as it was a "safety" trial (for a drug that's been on the market for about 40 yrs). There were allowing people on any CRAB do the trial though, in combination with LDN . . . which is contrary to Dr B's advice. It's great that it seems to have proven SAFE & effective (over 8 weeks) . . . but it doesn't prove it is more effective on it's own, in the long run, or combined with Copaxone.

There is more trial information on this site:

http://www.ldners.org/research.htm

You need to get all your ducks in a row, and not be impatient. It took me six months to wear down my doc, but it was worth the effort. I have a helpful link to help you prepare your case for your doctor, so please PM me if you want to read it.

Cherie
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