Interesting, I knew they were leaning on it for a while but now it looks like we have the strongest evidence that MS is genetic. I hope my mother does not find out, she already feels guilty that I have it. (her father had PPMS) and so do I.

http://www.nationalmssociety.org/res...008/index.aspx

Wow, for some reason this makes me sad because we have children. I aways knew it was a possibility but now we may know for sure. I went to the site to see if Jim could donate and he can't because his dad has passed away. I hope many here think about donating because it is history in the making. This could help so many including our children if it's proven.

Thanks for the info Earl.

Man......they are working at a snail's pace on this disease.

amen, Sally!

I participated in one of the first MS genetic studies, in the San Francisco Bay Area, geez, I think it was WAY back in 1992 or 1993...

my mother, my father, and four of my siblings, plus me, all did blood draws, and sent the vials in special boxes, via express mail.

I never heard what came of that study...

but yeah, even back then, they were pretty darn sure there was a genetic component to the disease, along with exposure to a triggering virus, living in certain lattitudes, and high sanitation standards.

they were particularly interested in our family, as my mother's aunt had MS (she passed away in the early 60s) and provided all the materials, postage, boxes, vials, and instructions.

my particular concern with MS and its genetic origins are due to the fact that my ex-husband's brother was dx'd with PPMS, 14 years ago, and is doing poorly.

this means that my son Benjamin has the "designer genes" on BOTH sides of his family.

I was told that the MS-carrying genes come from the mother's side, but still, it worries me, because it could mean the gene is reinforced in my son (he's now 24)

Very interesting. I was diagnosed a year ago this Saturday. My mother was diagnosed 2 months before I was and she is 23 years older than me. My neuro told me that unfortunately I hit the mother lode. 1) genetic risk since my mother has MS 2) vitamin D deficiency 3) grew up in a cold climate 4) a severe case of mono a year and a half before my diagnosis (viral trigger perhaps). Sigh.....

If there was a study I would try to have my mother sign up with me to assist with genetic research.

Duh!!! I just read this more closely. I should try to participate in the study with my mother.