But since many people here already do injections, it probably
is not so much of an issue.

The majority of injectable B12 is cyano version. If you are one
of the people who cannot convert it, then it doesn't work.

The oral active form methylcobalamin is so inexpensive and easy to use, and it has shown to be comparable to injection.

The only advantage I see for injection is for rapid intervention.
Often we see in the elderly when they are admitted to a long term care facility--very very low B12 levels. So injections are
given daily or every other day to get levels up quickly. Most of the B12 given by injection is cleared out of the blood within 72 hours. It is really a shame that the elderly might not even need the special care if they were targeted earlier. That is why NIH now recommends B12 supplementation for all people over 50, even if no symptoms exist yet.

There has always been a connection to low B12 and MS. In fact there were studies in Japan using mega mega doses up to 40mg a day for MSers-- That study is on PubMed. Many I believe are in the cloudy hard to diagnose category.

The anemia may not be due to low B12 or it may be. The type of anemia most often seen is a macrocytic anemia. MCV volume test reveals that. Anemia may be due to kidney problems, iron deficiency, malabsorption of iron, or hereditary reasons. If you are anemic it is often recommended to use a folic acid supplement, as well.

I just wanted to thank you all for this thread. I had my follow up appt a couple of weeks ago with my pcp. My bloodwork all came back normal. I had gone because my hair has been thinning and I wanted to know if it was my health or stress or the copaxone doing this to me. The bloodwork can back normal. However, he suggested trying an iron supplement due to history with anemia in my past, my 1st pregnancy.
While reading this thread, I decided to whip out my paperwork. B12-428. Ferritin -23. Pretty much, on paper, on the 'scales' I turn up 'healthy.' And for the most part, I agree I 'seem' healthy. But let's be real. I have MS. An often 'hidden' disease

Now that I've read this, I'm now certain as to what supplement I really should be taking.

Thank You, again, for this thread. Sometimes I believe that in life, there are no coincidences. It's no coincidence to me, tonight, why this thread is sitting here....

Wow, Gladys, sounds like your ferritin and B-12 are in the same ballpark as mine! I'm definitely going to take B-12 and am thinking about some iron if I can find a supplement that doesn't mess with my digestive system. I have read elsewhere that hair loss is often a sign of iron deficiency. And my hair has been falling out in large amounts off and on for the past 2 years. Just because the range of ferritin is 10-220 doesn't mean that 20 couldn't be low for me. Or 23 be low for you! Good luck with everything.