Dear Joan.

I am taking 1000mg of Citrulline daily (not the citrulline malate).

I am using the Source Naturals brand. I started with both, including arginine, but I don't think one really needs that every day, since most of it doesn't get past the GI tract. One day I did alot of bending in the garden, (when taking both) and I got a severe orthostatic reaction (I am still taking my blood pressure meds). So I dropped the arginine for now, and just use the citrulline.

I have noticed an improvement in muscle burning, my leg pain is much less, I can do stairs better, etc. It has not yet done much for my blood pressure. But the pounding heart I was getting in the middle of the night has gone away. My feet still get a little cold at night but not like before when they would actually hurt being cold. I've had cold feet ever since my thyroid retired. Even with hormone, they still get cold in the winter now.

The tablet is huge...hard for me to swallow. I have to zen myself into it, and place it with the pointy part back, and with a big swallow of water, toss it back. Otherwise sideways it seems to scrape all the way down! There are powder forms of this, so I might investigate that when the time comes to reorder.

Have you had your Vit D tested? Newest research is coming in daily about keeping serum levels at a good reading.
Here is a video on that:
http://www.youtube.com/watch?v=TQ-qekFoi-o

Hello and welcome, we are glad you found us.

Thanks, Mrs. D, for the information. I too am hypothyroid and take medication for that; also have reynauds. My vitamin D is in good shape--it should be as I take 5000 units of vit D/day--some even suggest taking more.

I have some L-Citrulline from Source Naturals too, but it is in capsule form, 500 mg each, so I will start taking 2. (They're not too big) Dr. Ignarro suggests 2-3000 mg of L-Arginine twice a day, and that seems like a lot. I'll wait and see how I do without adding it. I did notice that iHerb had a combination pill of both, but wasn't sure about it since the dosage was different.

Thanks again for your response.

Joan

Joan... there are creams designed for the feet, with arginine in them. I haven't tried them, because they also have capsacsin in them, and I hate that (the burning!).

But some can tolerate that.

We've had some discussion about the topical version at PN.
http://www.argininewellness.com/healthifeet.html

So far I am pleased with the l-citrulline. But it has only been
a month. I think that if one has circulatory problems in the feet, there are probably other body areas with constriction too.
Oral treatment therefore would be global and treat unseen issues. The topical would help only at the level applied.

Thanks for the tip, I will try it--I'll also check on the PN forum. Joan

I found other printed sources for citrulline dosing.

A Google book by Dr. Ignarro where he recommended 750mg citrulline daily.

I also found some other person who said to take both.
1000mg arginine + 750 citrulline.
(most amino acids need to be taken in gram amounts, BTW).

So I decided to do 1000mg of each.

I have sent you a PM (private message) too.

I will try 1000 of each too, and then we can compare reactions/benefits. My feet are either ice cold or burning--it would be nice if they were neutral!