So, what IS going on?

Conductor71 · 10-23-2010, 10:10 PM

Quote:

Originally Posted by reverett123

We are leaving neurology behind and entering the world of endocrinology. I am convinced that that is where PD lives. Yes, we have damage to particular parts of the brain, but the causes of that damage come from here as well as the immune system. Motor symptoms result from the latter's inflammatory response. Non-motor symptoms, however, are a child of the endocrine and stress.

Long neglected because neurology didn't consider it important, the endocrine system is all about stress and emotions. We all know what an effect these have on our symptoms, but we are only now starting to wonder what they were doing to us during those "pre-clinical" decades prior to that first tremor.

There is much here to lean.
-Rick

Ran across this phenomenon known as "apathetic thyrotoxicosis". In these case studies, people have symptoms opposite of the classic hyperthroid presentation. Note all patients express a sense of profound weakness; one could barely walk and another bedridden. It is noted that dopamine regulation of thyroid hormone levels plays a role.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955902/

pegleg · 10-24-2010, 02:27 AM

Sure looks like it outside and in these forums.

When the moon is full more babies are born (really), and kids' behavior gets negative (I know - taught for 15 years), and people like us PWP - with all of our huypersensitivity get . . . er . . . hypersensitive! lol

Did you note the date this thread began? 2006 ! And yet, it's just as applicable today as it was then - probably moreso!

I have been up all night - I broke down and chewed up one-half Sinemet to kee from wiping out, and I was drawn to this computer and to harley's post then this resurrected one.

As I wrote in my journal in 2000, (paraphrased) I don't believe in predestiniation. But I do believe there is a plan given to each of us. How we travel from point A to B is an individual choice.

I don't believe in predistination, but I do believe in windows of opportunity. Step through your window and someone, somewhere in time will benefit because we did.

I think I'll go out and howel at the moon

Peg

Bob Dawson · 10-24-2010, 05:50 AM

Quote:

Originally Posted by pegleg

I don't believe in predistination, but I do believe in windows of opportunity. Step through your window and someone, somewhere in time will benefit because we did.

I think I'll go out and howel at the moon

Peg

Stone coyotes say we were born to howl

And underneath the white moon rising
Something's stirring, on the prowl
Can you hear coyotes crying?
Singing, " We were born to howl"

We hail from an ancient dream
We heed a different call
We sing the song of things unseen
We sing for no reason at all

Bob Dawson · 10-24-2010, 01:18 PM

Quote:
There is much here to learn.
-Rick

Rick, this is one of many brilliant threads you have triggered. Remarkable. I just printed it up so I can go offline and read it again and take notes. I have had this disease for many-a-fortnight and did not know or question much about what it was; I would not have a clue without y'all.

EmptyNest68 · 10-25-2010, 12:51 PM

With all due respect (to the medical community), I think the leading researchers in the field of movement disorder and endocrinology could learn something from reading these posts.....

GregD · 10-25-2010, 03:09 PM

Quote:

Originally Posted by EmptyNest68

With all due respect (to the medical community), I think the leading researchers in the field of movement disorder and endocrinology could learn something from reading these posts.....

Won't ever happen, it's just thoes silly Parkies talking again.