Parkinson's Disease Tulip


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Old 04-07-2011, 10:14 AM #11
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Quercetin is found in abundance in apples, as in "an apple a day..."



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Originally Posted by reverett123 View Post
This potassium shift problem is going to render worthless anything I report in-so-far as the rest of us are concerned. If anyone else is testing this, any data would be particularly valuable.

Laura-
I noticed improvement the first day but I have not had another as good. I'll take a guess at what is going on, though- One of the claims for Qu is that it helps with insulin resistance. Anything that increases the flow of glucose from blood to cell may very well do the same with potassium, thus leading to our problem. Things that buffer insulin release (such as an egg for breakfast or "grazing" instead of having a meal) act to smooth things out.

Also, there is what is called "the dawn phenomenon". During the night, glucose and insulin both drop. Along about 6:00 AM and until 9 AM or so, our liver starts rebuilding the glucose levels in the blood and the pancreas starts upping the insulin to move that glucose into the cells. As a result of this our systems differ from morning to night and what works in morning behaves differently in evening.

Right now, I am taking the Qu at dinner and it has resulted in a much longer and improved evening for me. But if I try to start the day with it, then I'm shot for the morning. So I'm trying to get that sorted out. Two things- exercise timing should have a big impact and adrenaline as well. The former positively and the latter negatively.
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Old 04-07-2011, 01:17 PM #12
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Hello,
I have PN and prostate problems, have been taking the NOW brand Quercetin for over six months and and it great for bladder, pelvic,prostate pain.
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Old 04-07-2011, 04:32 PM #13
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Papaya , rhubarb have quercetin too and I wonder with all that since we have been eating them ...if that is one of the main ingredients that are helping our symptoms.
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Old 04-07-2011, 08:56 PM #14
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Default Today's report

Trying to get a bit more disciplined, today I took a single 800 mg capsule at 6:00 PM along with a single sinemet CR 50/200. A couple o weeks back that would have lasted just two hours. It is now 9:55 and other than some mild DK I am doing well.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 04-07-2011, 09:22 PM #15
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Rick, and Aunt Bean, I read somewhere that it is best to take these bioactive natural supplements separately from pharmaceutical medications, that their efficacy is reduced by the chemicals. I mention this because Rick said that he takes his with sinemet. I wonder if either of you had a view on this. I have not experimented sufficiently to know one way or another. They recommended leaving a two hour gap, something that is just about possible if wearing off is not too fast........

I have followed this thread with great interest, especially about the apple link as I had a sudden improvement following a couple of days of drinking (very expensive) organic fresh apple juice on special offer, very unexpected, and am thinking of looking for some quercetin. Goodness knows, the drugs we are prescribed do not enough for what we take them for, and too much that we would choose to lose.....

Lindy
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Old 04-07-2011, 09:34 PM #16
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Lindy-

Take a look back at my first post on this thread. They are talking about using it to increase the effectiveness of the synthetics and ascribing a joint MAOI and COMT inhibitor action against cataleptic rats. To me, the latter is similar to freezing.

I would like to know however, just how minimal doses of sinemet would affect things. And would just using it with our own dopamine stores do anything? -Rick


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Originally Posted by lindylanka View Post
Rick, and Aunt Bean, I read somewhere that it is best to take these bioactive natural supplements separately from pharmaceutical medications, that their efficacy is reduced by the chemicals. I mention this because Rick said that he takes his with sinemet. I wonder if either of you had a view on this. I have not experimented sufficiently to know one way or another. They recommended leaving a two hour gap, something that is just about possible if wearing off is not too fast........

I have followed this thread with great interest, especially about the apple link as I had a sudden improvement following a couple of days of drinking (very expensive) organic fresh apple juice on special offer, very unexpected, and am thinking of looking for some quercetin. Goodness knows, the drugs we are prescribed do not enough for what we take them for, and too much that we would choose to lose.....

Lindy
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 04-08-2011, 02:11 PM #17
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Took yesterday's last dose of sinemet plus quercetin at 6:00 PM. Went to bed still "on" at 11:00 PM. Good night's sleep.

Up at 7:30 AM. Took 1x Sinemet CR 50/200 plus 1x Sinemet 10/100 plus 1/2 capsule Qu (about 400 mg);

8:00 On (quick as it gets for me)

9:00 Hints of going "Off", repeated 7:30 dosing

9:15 Off

9:45 back On

11:00 Requip 8 mg

1:00 Sinemet CR 50/200; plus Sinemet 10/100

Currently 3:00 PM and On

Intent is to hold out until 4 PM and take Requp, then at 6 PM repeat last night.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 04-12-2011, 02:07 PM #18
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Default Time for an update

My pattern at present seems to be taking a single dose of 400 to 800 mg of quercetin plus 100 to 200 mg bromelain at about 6:00 PM. I take it with 1x Sinemet CR 50/200 plus 1x Sinemet 10/100. This allows me to have a normal evening and go to bed about 11:00 PM with no further medication. Read my initial posts to appreciate what an improvement that is.

There is more. It is almost 3:00 PM here. Thus far today, I have taken the following:
8:00 AM - 2x Requip 4 mg ea.
10:00 AM - 1x Sinemet CR 50/200 plus 1x Sinemet 10/100
and that is all. Again, take a look at the early posts.

Even now I don't feel a need for that third dose of the day, although I'm sure it will sneak up on me soon. At present I am moderately dyskinetic which I take as either too much ldopa available or sensitized receptors. Either is a signal to cut back even more.

Another thing of note is that my moribund GI tract has, over the last three days, begun to show signs of life. If that indicates a stirring in my autonomic nervous system then that may be big news. -Rick
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 04-12-2011, 05:54 PM #19
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Quote:
Originally Posted by reverett123 View Post
My pattern at present seems to be taking a single dose of 400 to 800 mg of quercetin plus 100 to 200 mg bromelain at about 6:00 PM. I take it with 1x Sinemet CR 50/200 plus 1x Sinemet 10/100. This allows me to have a normal evening and go to bed about 11:00 PM with no further medication. Read my initial posts to appreciate what an improvement that is.

There is more. It is almost 3:00 PM here. Thus far today, I have taken the following:
8:00 AM - 2x Requip 4 mg ea.
10:00 AM - 1x Sinemet CR 50/200 plus 1x Sinemet 10/100
and that is all. Again, take a look at the early posts.

Even now I don't feel a need for that third dose of the day, although I'm sure it will sneak up on me soon. At present I am moderately dyskinetic which I take as either too much ldopa available or sensitized receptors. Either is a signal to cut back even more.

Another thing of note is that my moribund GI tract has, over the last three days, begun to show signs of life. If that indicates a stirring in my autonomic nervous system then that may be big news. -Rick
your study in alchemy is paying off!! YAY! LOVE to hear this - do keep sharing your experiences! have you considered just going off requip first?
go guy
md
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Old 04-12-2011, 07:06 PM #20
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Default Just to finish up the day

My psychic powers were running true and about 3:15 a gnome with a large rubber mallet came up behind me and reminded me. So, I took 2x Requip 4 mg each. Took a little over an hour to come back on, but it is 8:00 PM and I am on with no further drugs including Qu. I think that I will take a half tablet of Sinemet CR 50/200 and a half cap of Qu and see if I can coast on in.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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