Parkinson's Disease Tulip


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Old 03-17-2007, 08:08 AM #1
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I took my dose of DM before bed last night and I feel great this morning!..Energetic, confident, fluid movement..a huge change from yesterday..I never feel this good, even cooincidentally without DM
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Old 03-17-2007, 08:54 AM #2
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Default Brand

Is there a specific brand you guys are using, or just any cough syrup with DM?
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Old 03-17-2007, 08:32 PM #3
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Default hate to rain on the party

Sorry but there is a problem. Monitor your blood pressure. I just got a reading of 175/105. Not good since I usually run about 140/90.

I'll watch it and let you know. It may vary from person to person too.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 03-17-2007, 09:59 PM #4
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Quote:
Originally Posted by reverett123 View Post
Sorry but there is a problem. Monitor your blood pressure. I just got a reading of 175/105. Not good since I usually run about 140/90.

I'll watch it and let you know. It may vary from person to person too.
This is what I found, but claims hypertension is a side effect of a 250-1000 mg dose..My BP runs on average about the same as yours, but havent checked mine lately..I have doubts that 5-8 mg would elevate BP

http://www.nhtsa.dot.gov/people/inju...methorphan.htm

Side Effect Profile: Adverse effects with recommended antitussive doses are rare. However, nausea, other gastrointestinal disturbances, slight drowsiness and dizziness can occur. Following acute doses of between 250-1500 mg, the following clinical and overdose symptoms have been reported: excitation, nausea, vomiting, drowsiness, dizziness, blurred vision, nystagmus, dilated pupils, body itching, rash, ataxia, sweating, hot/cold flashes, fever, hypertension, shallow respiration, urinary retention, diarrhea, opisthotonos (spasm where head and heels are bent back, and torso is bent forward), toxic psychosis (hyperactivity, marked visual and auditory hallucinations), coma, and an increase in heart rate, blood pressure and body temperature. Side effects can be serious if very large doses of the combined preparations are ingested; for example, guaifenesin and dextromethorphan can cause severe nausea and vomiting; chlorpheniramine and dextromethorphan can cause seizure, loss of consciousness and bleeding.
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Old 03-18-2007, 04:29 AM #5
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Default i suspect...

..that it may be an interaction with something else and I'll investigate further. Otherwise I've been impressed with the DM. Also, I do have high BP anyway and am on meds for that, so there may be a factor.

Even with all that, I have awakened at 5:00 AM. taken my meds, and am "on" at just 5:30. Usually there is an hour of thumb twiddling for me in the initial wait.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 03-18-2007, 07:45 AM #6
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Lightbulb excuse me...

but guaifenesin is NOT a decongestant. It is a mucolytic, and does not raise blood pressure. It may cause nausea however. It is often COMBINED with decongestants, so read labels carefully. Guaifenesin is typically used in heart patients and those with hypertension and is safe in that respect.

Also pediatric products contain mixtures of things as a rule, or are also long acting now.
Here is Robitussins new line:
http://www.robitussin.com/formula/index.asp
Robitussin maximum is no longer on the website...but it is still on Drugstore.com:
http://www.drugstore.com/products/pr...-PLST-0-SEARCH
This does not have guaifenesin in it.

DM interacts with SSRIs too. I posted that earlier in this thread. Not commonly but it does happen. I would expect it at higher doses of both drugs, and/or in slow metabolizers. People with abnormally high levels of serotonin physiologically would be at risk also, these include hidden tumors secreting biogenic amines (lung cancer) or undiagnosed carcinoid syndrome (often hidden and hard to diagnose).

But basically DM is easy to tolerate for most people.
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Old 03-20-2007, 11:22 AM #7
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Default Side effects

After research, reading the posts about good results others have had taking dextromethorphan, and finding a pediatric dose with no alcohol or other active ingredients, I took one/half teaspoon of Robitussin pediatric cough syrup before bedtime. I almost immediately felt a little queasy and one hour later was awake with a dry eye feeling and a rapid, rapid heartbeat. I tried to keep calm, but I kept thinking, "What the heck is this?" This morning I awoke feeling stiffer than ever. Everyone's PD is different, and I guess this medicine is not for me.

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Old 03-20-2007, 12:56 PM #8
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I tried something different last night..actually by accident..I usually take my last dose of Sinamet for the day at 7:00 pm, and I didnt remember to take it untill 11:30..I took the DM at 12:30, and am having a real good day today, all except for some weakness in my right wrist and forearm
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Old 03-20-2007, 01:57 PM #9
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Default each of us really is different

And since we are often taking different regimens we are even more so. In my case I have had to choose between the DM and some other supplements that have proven valuable and the latter have won out. One of the reasons they work is that some are natural MAO inhibitors and as a result are not compatable with the DM, much to my disappointment.

I don;t know what Steve takes besides his prescribed meds but it may be that DM is a good choice for those who don,t use a lot of other stuff that might react with it.

Steve do you take much other stuff? And what about you Ann? Just looking for patterns.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 03-20-2007, 02:27 PM #10
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Default Rick

I take;..

Sianmet 3x25/100

Mirapex 2x.25

I am definately undermedicated, and should at least take 1 more Sinamet daily

No suppliments, and I dont pay attention to my diet and have taken Sinamet just before or after eating protien or what have you
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