Parkinson's Disease Tulip


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Old 02-18-2009, 01:33 PM #20
girija girija is offline
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Join Date: Nov 2006
Location: southern tip of west coast
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15 yr Member
girija girija is offline
Member
 
Join Date: Nov 2006
Location: southern tip of west coast
Posts: 582
15 yr Member
Default Placebo needed or not: trying to understand

Good morning!
Thank you for a lot of thoughtful discussions this morning and I am trying classify them in my head. So please bear with me. It looks like (as some of you already pointed out), there are several issues to sham treatment, such as

1. Ethical issues related to Surgery
2. Ethical issues related to how informed are patients about "informed consent".
3. Emotional factors involved
4. Scientific rationale for doing sham surgery
5. FDA rules and regulations
6. Financial reasons

Obviously they are all tied together. But if we can come up with pros and cons for these points, we may come to some sort of an answer fo doing sham procedures. Thats my two cents worth on this topic!

Girija



Quote:
Originally Posted by jeanb View Post
For people who did well in the Ceregene trial, I wonder if the placebo effect were part of doing so well?

As others have stated earlier in this thread, placebo effect is very much present in our clinical trials.
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