It is hard to say how much Metronidazole would be absorbed.
The gel would facilitate it, I'd imagine.

I don't think enough would be systemic to be a factor, but, you never know with drugs:

http://www.rxlist.com/metrogel-drug.htm

Notice only 13 patients tested.

Hi
What do you do about the roscasca in your eyes? Eye doc wrote a script for Pataday, stops the itching for a while, but it always comes back the next day. I don't have many eye lashes left because of this! LOL

Barb, because my rosacea has been so sporadic over the years, I actually am not treating it with any medications and I never have. Just when it is about to drive me to the doctors, it settles down. My sister has it too and it affects her the same way...

The number of patients is typical of these companies. I'm amazed that the FDA approves these drugs with studies that small. I think I'm going to stop using it and go back to using the lotion I purchased that is an alternative type of treatment called Prosacea along with Eucerin and/or Cetaphil.

As for the other posts concerning eyes, I use artificial tears to help prevent the crusting which occurs as a result of Rosacea and to keep the eyes hydrated. In the winter, I use the gel form at bedtime since using heat dries the eyes and I find that the dryness aggravates the Rosacea. I use them as often as needed and this was suggested by my opthalmologist. The dermatologist has also prescribed doxycycline at times when its gotten out of hand but I find that I haven't had to use those when I regularly use drops/gels. Take care.

I developed a rash as well. It looked very similar to a Lupus rash execept it went into the folds of my nose/lip area as well as the usual malar rash area. It got horrible when I went off meds! Then it calmed down when I got off everything.....made me wonder if drug induced Lupus was going on?? They list drugs that cause lupus, however, there are many more.

I also took doxycycline.....not good with Lupus...and not good with sunshine!

Oh I also got big brown spots that are fading away now.

Makes ya wonder!