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-   -   Vitamin D and Peripheral Neuropathy: (https://www.neurotalk.org/peripheral-neuropathy/115722-vitamin-peripheral-neuropathy.html)

mrsD 05-19-2015 10:51 AM

Quote:

Originally Posted by EnglishDave (Post 1143181)
One thing you have to watch out for with vitamin D supplements is if you take the heart medications Diltiazem or Verapamil. There is something about the calcium absorbtion that reduces the effectiveness of these meds.

I take Diltiazem and become D deficient slowly over the year due to lack of sun (that's me, nothing to do with our weather:)).Under my GP I take D supplement for 3 months at the most while I level out - having interim blood tests for calcium levels. Then I have to stop for the remainder of the year.

Dave.

From what I see on several medical sites, use of calcium channel blockers with CALCIUM and high dose Vit D is not recommended. It is the calcium combos that get sited most often.

I don't see anything to suggest that moderate Vit D3 is a problem... say 2000IU a day or thereabouts. But taking calcium IS a problem. Really, the recommendations about taking high dose calcium has changed for men and women lately irregardless of Vit D intake... The high dose calcium lends to hardening of the arteries according to some new studies.

I took diltiazem for about 2 yrs as an add on for my blood pressure before I discovered magnesium lotion lowered me good enough to eliminate it and use only one agent, instead of 3. I used to get terrible leg cramps from it, and I never really liked it for that reason.

http://www.everydayhealth.com/heart-...l-blocker.aspx
There are several other sites with similar info out there.

juliejayne 05-19-2015 12:51 PM

Quote:

Originally Posted by mrsD (Post 1143150)
Some people have pain... we had one fellow with upper back pain.
He recovered with normalizing the D3.

You can have numbness or tingling on the face or around the mouth too, with low D.

There can be muscle issues, since calcium is needed for muscle contraction, and magnesium for relaxation. Both of these minerals are enhanced absorption with Vit D.

Low D. is thought to impair the immune system, so more frequent infections may occur when low. There are suggestions too about proper D levels discouraging cancer development (definite proof is still lacking on this one).

If you tested low, you should take it to normalize your levels.

That is what I thought, and as I said I have none of these symptoms. It seems that I have Vit D deficiency, with ZERO symptoms, and lots of symptoms of something else?

Tunaboy 05-19-2015 12:52 PM

My Vitamin D was on the lower end but still within range. Strange because I have been supplementing with D3 2000 iu long before all this started.

EnglishDave 05-19-2015 01:30 PM

MrsD,

I'm no expert, obviously, and until I came here I rarely questioned things - I even had no access to the Net before June last year, relying on family to check for contraindications of new meds.

Here is my own 'go to' site - being based in the UK - this is the page for Diltiazem.

http://www.nhs.uk/medicine-guides/pa...ase%20capsules

I know that, personally, taking a combination of the two does something to calcium levels in my blood which cause concern. Before I came here I was mentally unstimulated and took little notice of effects over Good/Bad. Therefore, I cannot even state which way my calcium levels went.

Dave.

mrsD 05-19-2015 01:40 PM

Going to a very good drugchecker....

Diltiazem + cholecalciferol == no interactions found

http://www.drugs.com/interactions-ch...st=646-0,890-0

Diltiazem + calcium carbonate == one moderate interaction
diltiazem ↔ calcium carbonate

Applies to: diltiazem, calcium carbonate

Quote:

Using diltiazem together with calcium carbonate can decrease the effects of diltiazem. Talk with your doctor before using diltiazem and calcium carbonate together. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
http://www.drugs.com/interactions-ch...st=464-0,890-0

Hence it is the calcium part of a combo pill and not the Vit D3 part.

It is confusing, I know. But I hope this clears it up some.

And as I mentioned before, the trend today is not to use so much calcium as a supplement anyway.

EnglishDave 05-19-2015 02:56 PM

Thanks MrsD,

I will remain slightly confused, but I have a follow-up question about the best source of vitamin D, natural sunlight. Here, from webmd:

Just 6 days of casual sunlight exposure without sunscreen can make up for 49 days of no sunlight exposure. Body fat acts like a kind of storage battery for vitamin D. During periods of sunlight, vitamin D is stored in fatty fat and then released when sunlight is gone.

Gives the basic mechanics, but do you know whether the body produces vitamin D if the sunlight is filtered through glass. I know that glass stops uv rays, is uv the trigger for production?

Dave.

mrsD 05-19-2015 04:24 PM

No..... glass filters out UV.... which is required for skin manufacture of D3. Also people using statins, will probably not convert in the skin, well or at all. There is some talk about elderly people losing the ability to make D3 in the skin due to age.

For all those on this thread who are new.... there is a D3 thread on our Vitamin forum here. I've been collecting all the newest news about it and treatment options...

http://neurotalk.psychcentral.com/thread92116.html

This D thread was made for the neuropathy/chronic pain aspect, but there is much more at the Vitamin forum.
Also there are several D3 threads mixed into the regular index of threads.

Kitt 05-19-2015 05:54 PM

An interesting article.

http://www.cnn.com/2012/07/10/living...to-sun-safety/

EnglishDave 05-19-2015 06:31 PM

MrsD,
I struggled through the Thread, one-eyed, some interesting stuff in there. I checked my meds Patient Info Sheet - no contraindications with D from them, BUT increases absorbtion of Atorvastatin - Aaargh!

Kitt,

A good article which made me dig deeper. Some (about 35-40%) of UVA can penetrate plain window glass. This, I assume, is reduced by thickness, double glazing.

And Fortified foodstuffs and Supplementation are not as widespread over here as one would like to think. So figures are probably worse for us in general.

Dave.

caroline2 07-02-2015 12:36 AM

I've been supplementing with D3 since end of 2006 when my sis brought this to my attention, she is challenged with MS....at that time I was feeling a lowness never thinking it was D deficiency. My lab came in at about 16 as I remember....got it up to 80 over a few years time and felt GOOD at 80, then went thru hip replacment in 2010 and that level dropped 40 pts with this surgery. I had read it could happen and sure enough it did. I have been working ever since to maintain 60+ Vit D.

Best to take K2 with D3 as this is the latest research...both are needed.


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